Probenecid Patent Expiration

Probenecid was first introduced by Merck And Co Inc in its drug Benemid on Approved Prior to Jan 1, 1982. 8 different companies have introduced drugs containing Probenecid.


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Clinical Trials

Recent Clinical Trials on Probenecid:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
The Re-Prosper HF Study VA Office of Research and Development NA COMPLETED
(Sep 1, 2026)
PHASE2, PHASE3
Drug-drug Interactions Studies of VC005 Tablets in Healthy Adult Subjects Jiangsu vcare pharmaceutical technology co., LTD NA NOT YET RECRUITING
(Aug 1, 2026)
PHASE1
Probenecid Administration for Alcohol Craving and Consumption Brown University NA RECRUITING
(Mar 1, 2026)
PHASE2


Probenecid Generic API Manufacturers

Several generic applications have been filed for Probenecid. The first generic version for Probenecid was by Lannett Co Inc and was approved on Approved Prior to Jan 1, 1982. And the latest generic version is by Rising Pharma Holdings Inc and was approved on Nov 20, 2023.

Given below is the list of companies who have filed for Probenecid generic, along with the locations of their manufacturing plants worldwide.