Ponatinib Hydrochloride is used for treating various types of leukemia, including acute lymphoblastic leukemia, chronic myeloid leukemia, and Philadelphia chromosome-positive acute lymphoblastic leukemia. It was first introduced by Takeda Pharmaceuticals Usa Inc in its drug Iclusig on Dec 14, 2012. 2 different companies have introduced drugs containing Ponatinib Hydrochloride.

Ponatinib Hydrochloride Patents

Given below is the list of patents protecting Ponatinib Hydrochloride, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in	Drug Patent Number	Drug Patent Title	Drug Patent Expiry	Drug Owner
Iclusig	US11192895	Crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide and its mono hydrochloride salt	Dec 12, 2033	Takeda Pharms Usa
Iclusig	US11192897	Crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide and its mono hydrochloride salt	Dec 12, 2033	Takeda Pharms Usa
Iclusig	US11384086	Crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1- yl)methyl]-3-(trifluoromethyl)phenyl}benzamide and its mono hydrochloride salt	Dec 12, 2033	Takeda Pharms Usa
Iclusig	US9493470	Crystalline forms of 3-(imidazo[1,2-B] pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl) methyl]-3-(trifluoromethyl)phenyl}benzamide and its mono hydrochloride salt	Dec 12, 2033	Takeda Pharms Usa
Iclusig	US8114874	Substituted acetylenic imidazo[1,2-B]pyridazine compounds as kinase inhibitors	Jan 24, 2027	Takeda Pharms Usa
Iclusig	US9029533	Substituted acetylenic imidazo[1,2-A]pyridazines as kinase inhibitors	Dec 22, 2026	Takeda Pharms Usa

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Ponatinib Hydrochloride's Family Patents

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Ponatinib Hydrochloride Generic API Manufacturers

Several generic applications have been filed for Ponatinib Hydrochloride.

Given below is the list of companies who have filed for Ponatinib Hydrochloride generic, along with the locations of their manufacturing plants worldwide.