Plerixafor Patent Expiration

Plerixafor is Used for mobilizing hematopoietic stem cells in patients with non-Hodgkin's lymphoma and multiple myeloma for autologous transplantation. It was first introduced by Genzyme Corp in its drug Mozobil on Dec 15, 2008. 10 different companies have introduced drugs containing Plerixafor.


Plerixafor Patents

Given below is the list of patents protecting Plerixafor, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Mozobil US6987102 Methods to mobilize progenitor/stem cells Jul 22, 2023

(Expired)

Genzyme
Mozobil US7897590 Methods to mobilize progenitor/stem cells Jul 22, 2023

(Expired)

Genzyme
Mozobil USRE42152 Aromatic-linked polyamine macrocyclic compounds with anti-HIV activity Dec 10, 2018

(Expired)

Genzyme



Plerixafor's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Plerixafor:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS National Institute of Allergy and Infectious Diseases (NIAID) NA COMPLETED
(Sep 17, 2026)
PHASE1, PHASE2
Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma City of Hope Medical Center NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE1, PHASE2
Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease City of Hope Medical Center NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE1
Stem Cell Mobilization and Apheresis for Life-threatening Blood Disorders St. Jude Children's Research Hospital NA NOT YET RECRUITING
(Aug 1, 2026)
PHASE1
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models National Institute of Allergy and Infectious Diseases (NIAID) NA RECRUITING
(Jul 30, 2026)
PHASE2
Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma City of Hope Medical Center NA ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE1
Protocol Title: Safety and Feasibility of Autologous CD34+ Hematopoietic Stem Cells Mobilization and Apheresis in Participants With RUNX1 Familial Platelet Disorder M.D. Anderson Cancer Center NA RECRUITING
(Jun 1, 2026)
PHASE1
Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia National Heart, Lung, and Blood Institute (NHLBI) NA ACTIVE NOT RECRUITING
(Mar 10, 2026)
PHASE1, PHASE2


Plerixafor Generic API Manufacturers

Several generic applications have been filed for Plerixafor. The first generic version for Plerixafor was by Dr Reddys Laboratories Ltd and was approved on Jul 24, 2023. And the latest generic version is by Hetero Labs Ltd Unit Vi and was approved on Jun 16, 2025.

Given below is the list of companies who have filed for Plerixafor generic, along with the locations of their manufacturing plants worldwide.