Pirfenidone Patent Expiration

Pirfenidone is used for treating idiopathic pulmonary fibrosis. It was first introduced by Genentech Inc in its drug Esbriet on Oct 15, 2014. 15 different companies have introduced drugs containing Pirfenidone.


Pirfenidone Patents

Given below is the list of patents protecting Pirfenidone, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Esbriet US10188637 Granulate formulation of 5-methyl-1-phenyl-2-(1H)-pyridone and method of making the same Mar 28, 2037 Genentech Inc
Esbriet US8778947 Methods of administering pirfenidone therapy Aug 30, 2033 Genentech Inc
Esbriet US7816383 Methods of administering pirfenidone therapy Jan 08, 2030 Genentech Inc
Esbriet US7910610 Methods of administering pirfenidone therapy Jan 08, 2030 Genentech Inc
Esbriet US8013002 Methods of administering pirfenidone therapy Jan 08, 2030 Genentech Inc
Esbriet US8084475 Pirfenidone therapy and inducers of cytochrome P450 Jan 08, 2030 Genentech Inc
Esbriet US8318780 Methods of administering pirfenidone therapy Jan 08, 2030 Genentech Inc
Esbriet US8648098 Pirfenidone therapy and inducers of cytochrome P450 Jan 08, 2030 Genentech Inc
Esbriet US8754109 Pirfenidone therapy and inducers of cytochrome P450 Jan 08, 2030 Genentech Inc
Esbriet US7566729 Modifying pirfenidone treatment for patients with atypical liver function Apr 22, 2029 Genentech Inc
Esbriet US7635707 Pirfenidone treatment for patients with atypical liver function Apr 22, 2029 Genentech Inc
Esbriet US8592462 Pirfenidone treatment for patients with atypical liver function Apr 22, 2029 Genentech Inc
Esbriet US8609701 Pirfenidone treatment for patients with atypical liver function Apr 22, 2029 Genentech Inc
Esbriet US8383150 Granulate formulation of pirfenidone and pharmaceutically acceptable excipients May 10, 2028 Genentech Inc
Esbriet US7696236 Method of providing pirfenidone therapy to a patient Dec 18, 2027 Genentech Inc
Esbriet US7696326 Multiple antigen glycopeptide carbohydrate, vaccine comprising the same and use thereof Dec 18, 2027 Genentech Inc
Esbriet US7767700 Method of providing pirfenidone therapy to a patient Dec 18, 2027 Genentech Inc
Esbriet US8420674 Method of providing pirfenidone therapy to a patient Dec 18, 2027 Genentech Inc
Esbriet US7767225 Capsule formulation of pirfenidone and pharmaceutically acceptable excipients Sep 22, 2026 Genentech Inc
Esbriet US7988994 Capsule formulation of pirfenidone and pharmaceutically acceptable excipients Sep 22, 2026 Genentech Inc
Esbriet US8753679 Capsule formulation of pirfenidone and pharmaceutically acceptable excipients Sep 22, 2026 Genentech Inc
Esbriet US9561217 Pharmaceutical composition containing as an active ingredient 5-methyl-1-phenyl-2-(1H)-pyridone Jan 25, 2022

(Expired)

Genentech Inc



Pirfenidone's Family Patents

Family Patents

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Pirfenidone Generic API Manufacturers

Several generic applications have been filed for Pirfenidone. The first generic version for Pirfenidone was by Amneal Eu Ltd and was approved on Jan 3, 2022. And the latest generic version is by Macleods Pharmaceuticals Ltd and was approved on Dec 18, 2024.

Given below is the list of companies who have filed for Pirfenidone generic, along with the locations of their manufacturing plants worldwide.