Lubiprostone Patent Expiration

Lubiprostone is Used for treating constipation, irritable bowel syndrome, and abdominal discomfort associated with irritable bowel syndrome. It was first introduced by Sucampo Pharma Americas Llc in its drug Amitiza on Jan 31, 2006. 7 different companies have introduced drugs containing Lubiprostone.


Lubiprostone Patents

Given below is the list of patents protecting Lubiprostone, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Amitiza US8026393 Soft-gelatin capsule formulation Oct 25, 2027 Sucampo Pharma Llc
Amitiza US8338639 Soft-gelatin capsule formulation Jan 23, 2027 Sucampo Pharma Llc
Amitiza US8779187 Soft-gelatin capsule formulation Jan 23, 2027 Sucampo Pharma Llc
Amitiza US8748481 Method for treating gastrointestinal disorder Sep 01, 2025 Sucampo Pharma Llc
Amitiza US7795312 Method for treating abdominal discomfort Sep 17, 2024

(Expired)

Sucampo Pharma Llc
Amitiza US6982283 Method for treating drug-induced constipation Dec 04, 2022

(Expired)

Sucampo Pharma Llc
Amitiza US8097653 Dosage unit comprising a prostaglandin analog for treating constipation Nov 14, 2022

(Expired)

Sucampo Pharma Llc
Amitiza US8389542 Dosage unit comprising a prostaglandin analog for treating constipation Nov 14, 2022

(Expired)

Sucampo Pharma Llc
Amitiza US7064148 Chloride channel opener Aug 30, 2022

(Expired)

Sucampo Pharma Llc
Amitiza US8088934 Composition and method for stabilizing the same May 18, 2021

(Expired)

Sucampo Pharma Llc
Amitiza US6583174 Composition and method for stabilizing the same Oct 16, 2020

(Expired)

Sucampo Pharma Llc
Amitiza US7417067 Composition and method for stabilizing the same Oct 16, 2020

(Expired)

Sucampo Pharma Llc
Amitiza US8097649 Composition and method for stabilizing the same Oct 16, 2020

(Expired)

Sucampo Pharma Llc
Amitiza US6414016 Anti-constipation composition Sep 05, 2020

(Expired)

Sucampo Pharma Llc
Amitiza US8071613 Anti-constipation composition Sep 05, 2020

(Expired)

Sucampo Pharma Llc
Amitiza US8114890 Anti-constipation composition Sep 05, 2020

(Expired)

Sucampo Pharma Llc
Amitiza US5284858 Prostaglandins E and anti ulcers containing same Jul 14, 2014

(Expired)

Sucampo Pharma Llc



Lubiprostone's Family Patents

Family Patents

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Lubiprostone Generic API Manufacturers

Several generic applications have been filed for Lubiprostone. The first generic version for Lubiprostone was by Amneal Pharmaceuticals Llc and was approved on Nov 30, 2021. And the latest generic version is by Ascent Pharmaceuticals Inc and was approved on Jan 2, 2025.

Given below is the list of companies who have filed for Lubiprostone generic, along with the locations of their manufacturing plants worldwide.