Leucovorin Calcium Patent Expiration

Leucovorin Calcium was first introduced by Hospira Inc in its drug Leucovorin Calcium on Approved Prior to Jan 1, 1982. Other drugs containing Leucovorin Calcium are Wellcovorin, Vykoura. 27 different companies have introduced drugs containing Leucovorin Calcium.


Leucovorin Calcium Patents

Given below is the list of patents protecting Leucovorin Calcium, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Vykoura US12564592 Dec 23, 2044 Avyxa Holdings



Leucovorin Calcium's Family Patents

Family Patents

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Leucovorin Calcium Generic API Manufacturers

Several generic applications have been filed for Leucovorin Calcium. The first generic version for Leucovorin Calcium was by Glaxosmithkline and was approved on Oct 19, 1982. And the latest generic version is by Gland Pharma Ltd and was approved on Nov 12, 2025.

Given below is the list of companies who have filed for Leucovorin Calcium generic, along with the locations of their manufacturing plants worldwide.