Ibuprofen was first introduced by Mcneil Consumer Healthcare Div Mcneil Ppc Inc in its drug Motrin on Approved Prior to Jan 1, 1982. Other drugs containing Ibuprofen are Children'S Advil-Flavored, Rufen, Motrin Ib, Advil, Advil Liqui-Gels, Motrin Migraine Pain, Midol Liquid Gels, Infant'S Advil, Pediatric Advil, Children'S Advil, Nuprin, Advil Migraine Liqui-Gels, Junior Strength Advil, Children'S Motrin, Children'S Elixsure, Caldolor, Ibu, Junior Strength Motrin. 71 different companies have introduced drugs containing Ibuprofen.

Ibuprofen Patents

Given below is the list of patents protecting Ibuprofen, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in	Drug Patent Number	Drug Patent Title	Drug Patent Expiry	Drug Owner
Caldolor	US11806400	Injectable ibuprofen formulation	Mar 16, 2032	Cumberland Pharms
Caldolor	US9072661	Injectable ibuprofen formulation	Mar 16, 2032	Cumberland Pharms
Caldolor	US9072710	Injectable ibuprofen formulation	Mar 16, 2032	Cumberland Pharms
Caldolor	US9012508	Administration of intravenous ibuprofen	Sep 14, 2030	Cumberland Pharms
Caldolor	US8735452	Treating patients with intravenous ibuprofen	Sep 30, 2029	Cumberland Pharms
Caldolor	US8871810	Treating critically ill patients with intravenous ibuprofen	Sep 30, 2029	Cumberland Pharms
Caldolor	US9114068	Treating patients with intravenous ibuprofen	Sep 30, 2029	Cumberland Pharms
Caldolor	US9138404	Treating critically ill patients with intravenous ibuprofen	Sep 30, 2029	Cumberland Pharms
Caldolor	US9295639	Treating critically ill patients with intravenous ibuprofen	Sep 30, 2029	Cumberland Pharms
Caldolor	US9649284	Treating critically ill patients with intravenous ibuprofen	Sep 30, 2029	Cumberland Pharms
Children's Advil-flavored	US10238640	Pharmaceutical suspension composition	May 25, 2024 (Expired)	Haleon Us Holdings
Caldolor	US6727286	Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid	Nov 27, 2021 (Expired)	Cumberland Pharms
Midol Liquid Gels	US6251426	Ibuprofen-containing softgels	Jun 25, 2018 (Expired)	Bionpharma

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Ibuprofen's Family Patents

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Ibuprofen Generic API Manufacturers

Several generic applications have been filed for Ibuprofen. The first generic version for Ibuprofen was by Basf Corp and was approved on Feb 8, 1985. And the latest generic version is by Pai Holdings Llc Dba Pharmaceutical Associates Inc and was approved on Nov 8, 2024.

Given below is the list of companies who have filed for Ibuprofen generic, along with the locations of their manufacturing plants worldwide.