Hydroxocobalamin Patent Expiration

Hydroxocobalamin is Used for the treatment of cyanide poisoning. It was first introduced by Btg International Inc in its drug Cyanokit on Dec 15, 2006. 6 different companies have introduced drugs containing Hydroxocobalamin.


Hydroxocobalamin Patents

Given below is the list of patents protecting Hydroxocobalamin, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Cyanokit US5834448 Dosage form of hydroxocobalamin and its use in cyanide poisoning Nov 14, 2016

(Expired)

Btg Intl



Hydroxocobalamin's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Hydroxocobalamin:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
Detoxification of the Liver In PSC (Dolphin) Brigham and Women's Hospital NA RECRUITING
(Jul 1, 2026)
PHASE2
A Study on Hydroxocobalamin Given to Healthy Individual to Monitor Symptoms Brigham and Women's Hospital NA COMPLETED
(Mar 1, 2026)
PHASE1


Hydroxocobalamin Generic API Manufacturers

Several generic applications have been filed for Hydroxocobalamin. The first generic version for Hydroxocobalamin was by Bel Mar Laboratories Inc and was approved on Approved Prior to Jan 1, 1982. And the latest generic version is by Abraxis Pharmaceutical Products and was approved on Approved Prior to Jan 1, 1982.

Given below is the list of companies who have filed for Hydroxocobalamin generic, along with the locations of their manufacturing plants worldwide.