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Glyburide; Metformin Hydrochloride Patent Expiration

Glyburide; Metformin Hydrochloride is Used for managing blood sugar levels in individuals with type 2 diabetes. It was first introduced by Bristol Myers Squibb in its drug Glucovance on Jul 31, 2000. 7 different companies have introduced drugs containing Glyburide; Metformin Hydrochloride.


Glyburide; Metformin Hydrochloride Patents

Given below is the list of patents protecting Glyburide; Metformin Hydrochloride, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Glucovance US6303146

(Pediatric)

 Solid oral dosage form comprising a combination of metformin and glibenclamide Jan 14, 2020

(Expired)

 Bristol Myers Squibb
Glucovance US6303146 Solid oral dosage form comprising a combination of metformin and glibenclamide Jul 14, 2019

(Expired)

 Bristol Myers Squibb



Glyburide; Metformin Hydrochloride's Family Patents

Family Patents

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Glyburide; Metformin Hydrochloride Generic API Manufacturers

Several generic applications have been filed for Glyburide; Metformin Hydrochloride. The first generic version for Glyburide; Metformin Hydrochloride was by Impax Laboratories Inc and was approved on Feb 18, 2004. And the latest generic version is by Zydus Pharmaceuticals Usa Inc and was approved on Feb 29, 2016.

Given below is the list of companies who have filed for Glyburide; Metformin Hydrochloride generic, along with the locations of their manufacturing plants worldwide.


1. ACTAVIS ELIZABETH

Actavis Elizabeth Llc has filed for 3 different strengths of generic version for Glyburide; Metformin Hydrochloride. All of these versions come by the name GLYBURIDE AND METFORMIN HYDROCHLORIDE. Given below are the details of the strengths of this generic introduced by Actavis Elizabeth.

Strength Dosage Form Availability Application Pathway TE code Launch Date
1.25MG; 250MG

tablet Prescription ORAL AB Jun 28, 2005
5MG; 500MG

tablet Prescription ORAL AB Jun 28, 2005
2.5MG; 500MG

tablet Prescription ORAL AB Jun 28, 2005


Manufacturing Plant Locations
New

Actavis Elizabeth's manufacturing plants are situated in 1 country - United States. Given below are the details of these plant locations as well as the firm names of Actavis Elizabeth as present at those locations.

Country City Firm Name
United States
Elizabeth Actavis Elizabeth LLC, A Company of Teva





2. AUROBINDO PHARMA

Aurobindo Pharma Ltd has filed for 3 different strengths of generic version for Glyburide; Metformin Hydrochloride. All of these versions come by the name GLYBURIDE AND METFORMIN HYDROCHLORIDE. Given below are the details of the strengths of this generic introduced by Aurobindo Pharma.

Strength Dosage Form Availability Application Pathway TE code Launch Date
1.25MG; 250MG

tablet Prescription ORAL AB Nov 14, 2007
2.5MG; 500MG

(reference standard)

tablet Prescription ORAL AB Nov 14, 2007
5MG; 500MG

tablet Prescription ORAL AB Nov 14, 2007


Manufacturing Plant Locations
New

Aurobindo Pharma's manufacturing plants are situated in 2 countries - India, United States. Given below are the details of these plant locations as well as the firm names of Aurobindo Pharma as present at those locations.

Country City Firm Name
India
Polepally, Mahaboob Nagar Aurobindo Pharma Limited
Medchal Aurobindo Pharma Ltd
Sangareddy Aurobindo Pharma Limited
Bachupally Aurobindo Pharma Limited
United States
East Windsor Aurobindo Pharma USA Inc





3. HERITAGE

Heritage Pharmaceuticals Inc Dba Avet Pharmaceuticals Inc has filed for 3 different strengths of generic version for Glyburide; Metformin Hydrochloride. All of these versions come by the name GLYBURIDE AND METFORMIN HYDROCHLORIDE. Given below are the details of the strengths of this generic introduced by Heritage.

Strength Dosage Form Availability Application Pathway TE code Launch Date
1.25MG; 250MG

tablet Prescription ORAL AB Jun 3, 2009
2.5MG; 500MG

tablet Prescription ORAL AB Jun 3, 2009
5MG; 500MG

tablet Prescription ORAL AB Jun 3, 2009


Manufacturing Plant Locations
New

Heritage's manufacturing plants are situated in 1 country - United States. Given below are the details of these plant locations as well as the firm names of Heritage as present at those locations.

Country City Firm Name
United States
Canfield Heritage Cooperative
Mc Cutchenville Heritage Cooperative, Inc
West Liberty Heritage Cooperative, Inc
New Philadelphia Heritage Cooperative
Ada Heritage Cooperative Inc
Springfield Heritage Cooperative, Inc
Woodsfield Heritage Cooperative
Van Nuys Heritage Candy Company, Inc.
Morgantown Heritage Animal Hospital
Sacramento Heritage Baking Company Inc.
Cairo Heritage Cooperative
London Heritage Cooperative Inc.
Minneapolis Heritage Deli Provisions, LLC
Waterford Heritage Cooperative
Fletcher Heritage Cooperative Inc
Kenton Heritage Cooperative
London Heritage Cooperative, Inc
South Burlington Heritage Aviation
Caldwell Heritage Country Store-Heritage Cooperative
Alger Heritage Cooperative
Urbana Heritage Cooperative Inc
West Mansfield Heritage Cooperative Inc.
Lisbon Heritage Cooperative, Inc.
De Graff Heritage Cooperative Inc
Beloit Heritage Cooperative
Chino Heritage #2
Richwood Heritage Cooperative, Inc
Vanlue Heritage Cooperative
Middlebury Heritage Acres
Dola Heritage Cooperative Inc
Fort Scott Heritage Acres Farm
Plain City Heritage Cooperative Inc.
Upper Sandusky Heritage Cooperative





4. IMPAX LABS INC

Impax Laboratories Inc has filed for 3 different strengths of generic version for Glyburide; Metformin Hydrochloride. All of these versions come by the name GLYBURIDE AND METFORMIN HYDROCHLORIDE. Given below are the details of the strengths of this generic introduced by Impax Labs Inc.

Strength Dosage Form Availability Application Pathway TE code Launch Date
1.25MG; 250MG

tablet Discontinued ORAL N/A Nov 19, 2004
2.5MG; 500MG

tablet Discontinued ORAL N/A Nov 19, 2004
5MG; 500MG

tablet Discontinued ORAL N/A Nov 19, 2004





5. TEVA

Teva Pharmaceuticals Usa Inc has filed for 3 different strengths of generic version for Glyburide; Metformin Hydrochloride. All of these versions come by the name GLYBURIDE AND METFORMIN HYDROCHLORIDE. Given below are the details of the strengths of this generic introduced by Teva.

Strength Dosage Form Availability Application Pathway TE code Launch Date
1.25MG; 250MG

tablet Discontinued ORAL N/A Jan 27, 2005
2.5MG; 500MG

tablet Discontinued ORAL N/A Jan 27, 2005
5MG; 500MG

tablet Discontinued ORAL N/A Jan 27, 2005


Manufacturing Plant Locations
New

Teva's manufacturing plants are situated in 6 countries - United States, India, Canada, Czech Republic, Ireland, Israel. Given below are the details of these plant locations as well as the firm names of Teva as present at those locations.

Country City Firm Name
United States
Horsham Teva Branded Pharmaceutical Products R&D
Malvern Teva Branded Pharmaceutical Products R&D, Inc.
Fort Dodge TEVA Animal Health Inc
Miami Teva Branded Pharmaceutical Products R & D, Inc.
India
Gajraula, Amroha Teva API India Private Ltd.
Bhind Teva API India Ltd- Malanpur
Canada
Markham Teva Canada Limited
Scarborough Teva Canada Limited
Stouffville Teva Canada Limited
Czech Republic
Opava Teva Czech Industries s.r.o.
Ireland
Dundalk Teva Laboratories Ireland Ltd
Israel
Kiryat-Shmona TEVA Medical Ltd.





6. ZYDUS PHARMS

Zydus Pharmaceuticals Usa Inc has filed for 3 different strengths of generic version for Glyburide; Metformin Hydrochloride. All of these versions come by the name GLYBURIDE AND METFORMIN HYDROCHLORIDE. Given below are the details of the strengths of this generic introduced by Zydus Pharms.

Strength Dosage Form Availability Application Pathway TE code Launch Date
1.25MG; 250MG

tablet Prescription ORAL AB Feb 29, 2016
2.5MG; 500MG

tablet Prescription ORAL AB Feb 29, 2016
5MG; 500MG

tablet Prescription ORAL AB Feb 29, 2016