Ezetimibe; Simvastatin Patent Expiration

Ezetimibe; Simvastatin is Used for treating high cholesterol levels in mammals, including primary hypercholesterolemia, mixed hyperlipidemia, and homozygous familial hypercholesterolemia (HoFH). It was first introduced by Organon Llc A Sub Of Organon And Co in its drug Vytorin on Jul 23, 2004. 10 different companies have introduced drugs containing Ezetimibe; Simvastatin.


Ezetimibe; Simvastatin Patents

Given below is the list of patents protecting Ezetimibe; Simvastatin, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Vytorin USRE37721

(Pediatric)

Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents Apr 25, 2017

(Expired)

Organon
Vytorin USRE42461

(Pediatric)

Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents Apr 25, 2017

(Expired)

Organon
Vytorin USRE37721 Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents Oct 25, 2016

(Expired)

Organon
Vytorin USRE42461 Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents Oct 25, 2016

(Expired)

Organon
Vytorin US5846966

(Pediatric)

Combinations of hydroxy-substituted azetidinone compounds and HMG CoA Reductase Inhibitors Mar 21, 2014

(Expired)

Organon
Vytorin US5846966 Combinations of hydroxy-substituted azetidinone compounds and HMG CoA Reductase Inhibitors Sep 21, 2013

(Expired)

Organon



Ezetimibe; Simvastatin's Family Patents

Family Patents

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Ezetimibe; Simvastatin Generic API Manufacturers

Several generic applications have been filed for Ezetimibe; Simvastatin. The first generic version for Ezetimibe; Simvastatin was by Ani Pharmaceuticals Inc and was approved on Apr 26, 2017. And the latest generic version is by Torrent Pharmaceuticals Ltd and was approved on Jan 27, 2025.

Given below is the list of companies who have filed for Ezetimibe; Simvastatin generic, along with the locations of their manufacturing plants worldwide.