Duvelisib Patent Expiration

Duvelisib is Used for treating chronic lymphocytic leukemia, small lymphocytic leukemia, and follicular lymphoma. It was first introduced by Secura Bio Inc in its drug Copiktra on Sep 24, 2018.


Duvelisib Patents

Given below is the list of patents protecting Duvelisib, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Copiktra US12213983 Treatment of cancers using PI3 kinase isoform modulators Apr 26, 2035 Secura
Copiktra US8193182 Substituted isoquinolin-1(2H)-ones, and methods of use thereof Sep 24, 2032 Secura
Copiktra USRE46621 Processes for preparing isoquinolinones and solid forms of isoquinolinones May 17, 2032 Secura
Copiktra US11312718 Formulations of (S)-3-(1-(9H-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one Jan 10, 2032 Secura
Copiktra US9840505 Solid forms of (S)-3-(1-(9H-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1 (2H)-one and methods of use thereof Jan 10, 2032 Secura
Copiktra US9216982 Certain chemical entities, compositions and methods Jan 05, 2029 Secura



Duvelisib's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Duvelisib:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
A Study of Ruxolitinib and Duvelisib in People With Lymphoma Memorial Sloan Kettering Cancer Center NA RECRUITING
(Sep 1, 2026)
PHASE1
Duvelisib Following Chimeric Antigen Receptor T-Cell Therapy Washington University School of Medicine NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1
Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas City of Hope Medical Center NA RECRUITING
(Aug 1, 2026)
PHASE2
Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL) Jonsson Comprehensive Cancer Center NA RECRUITING
(Jul 1, 2026)
PHASE1, PHASE2
A Study of Topical Duvelisib in Participants With Early-stage Mycosis Fungoides SecuraBio NA NOT YET RECRUITING
(Jul 1, 2026)
PHASE1
Duvelisib and Nivolumab for the Treatment of Stage IIB-IVB Mycosis Fungoides and Sezary Syndrome National Cancer Institute (NCI) NA ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE1
Duvelisib Maintenance After Autologous Stem Cell Transplant in T-Cell Lymphomas Washington University School of Medicine NA TERMINATED
(May 1, 2026)
PHASE2
Prospective, Single Arm, Single Center Study of Duvelisib Combined With Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma (PTCL) Liling Zhang NA RECRUITING
(May 1, 2026)
PHASE2
A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL) Memorial Sloan Kettering Cancer Center NA RECRUITING
(May 1, 2026)
PHASE1
A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype SecuraBio NA RECRUITING
(Apr 1, 2026)
PHASE3
Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS Dana-Farber Cancer Institute NA ACTIVE NOT RECRUITING
(Mar 1, 2026)
PHASE1, PHASE2


Duvelisib Generic API Manufacturers

Given below is the list of companies who have filed for Duvelisib generic, along with the locations of their manufacturing plants worldwide.