Deucravacitinib Patent Expiration

Deucravacitinib is Used for treating moderate-to-severe plaque psoriasis in adults who may benefit from systemic therapy or phototherapy. It was first introduced by Bristol Myers Squibb Co in its drug Sotyktu on Sep 9, 2022.


Deucravacitinib Patents

Given below is the list of patents protecting Deucravacitinib, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Sotyktu US12521390 Dosage Forms For Tyk2 Inhibitors Feb 11, 2043 Bristol
Sotyktu US10000480 Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses Nov 07, 2033 Bristol
Sotyktu US11021475 Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses Nov 07, 2033 Bristol
Sotyktu USRE47929 Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFNα responses Nov 07, 2033 Bristol



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Deucravacitinib's patents.

Given below is the list recent legal activities going on the following patents of Deucravacitinib.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 8th Year, Large Entity 03 Dec, 2025 US10000480
Payment of Maintenance Fee, 4th Year, Large Entity 13 Nov, 2024 US11021475
Payment of Maintenance Fee, 4th Year, Large Entity 01 Dec, 2021 US10000480
Patent Issue Date Used in PTA Calculation 01 Jun, 2021 US11021475
Sequence Moved to Public Database 01 Jun, 2021 US11021475
Recordation of Patent Grant Mailed 01 Jun, 2021 US11021475
Issue Notification Mailed 12 May, 2021 US11021475
Dispatch to FDC 04 May, 2021 US11021475
Letter Accepting Correction of Inventorship Under Rule 1.48 03 May, 2021 US11021475
Application Is Considered Ready for Issue 03 May, 2021 US11021475


Deucravacitinib's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Deucravacitinib:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis Bristol-Myers Squibb NA RECRUITING
(Sep 1, 2026)
PHASE3
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK) Bristol-Myers Squibb NA RECRUITING
(Sep 1, 2026)
PHASE3
A Clinical Trial of TQH3906 Capsules in Adult Patients With Moderate to Severe Plaque Psoriasis Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. NA RECRUITING
(Sep 1, 2026)
PHASE3
Continued Access to Deucravacitinib for Adult SLE/SjD and Pediatric PsO/PsA Study Completers Bristol-Myers Squibb NA NOT YET RECRUITING
(Sep 1, 2026)
PHASE3
Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis Bristol-Myers Squibb NA COMPLETED
(Aug 1, 2026)
PHASE3
A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque Psoriasis Bristol-Myers Squibb NA RECRUITING
(Aug 1, 2026)
PHASE3
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment Bristol-Myers Squibb NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE3
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs Bristol-Myers Squibb NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE3
A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis Janssen Research & Development, LLC NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE3
A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2) Janssen Research & Development, LLC NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE3
Deucravacitinib (BMS-986165) for Pityriasis Rubra Pilaris Mayo Clinic NA COMPLETED
(Aug 1, 2026)
PHASE2
A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic Arthritis Bristol-Myers Squibb NA RECRUITING
(Aug 1, 2026)
PHASE3
Deucravacitinib in the Treatment of Cicatricial Alopecias Icahn School of Medicine at Mount Sinai NA RECRUITING
(Jul 1, 2026)
PHASE2
Evaluating the Safety and Efficacy of Deucravacitinib Compared to Placebo Hidradenitis Suppurativa (HS). Beth Israel Deaconess Medical Center NA TERMINATED
(May 1, 2026)
PHASE2
Vitiligo Treatment by Targeting TYK2 Mediated Responses Centre Hospitalier Universitaire de Nice NA ACTIVE NOT RECRUITING
(May 1, 2026)
PHASE2
A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque Psoriasis Takeda NA COMPLETED
(Apr 1, 2026)
PHASE3


Deucravacitinib Generic API Manufacturers

Given below is the list of companies who have filed for Deucravacitinib generic, along with the locations of their manufacturing plants worldwide.


Deucravacitinib News

BMY Concentrates on Expanding Drug Labels: Can This Stimulate Growth? - The Globe and Mail

13 Jun, 2025

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