Copper Patent Expiration

Copper was first introduced by Gd Searle Llc in its drug Cu-7 on Approved Prior to Jan 1, 1982. Other drugs containing Copper are Tatum-T, Miudella, Paragard T 380A. 3 different companies have introduced drugs containing Copper.


Copper Patents

Given below is the list of patents protecting Copper, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Miudella US10918516 Intrauterine device with controlled copper ion elution Jan 23, 2037 Sebela Womens Hlth
Miudella US11207209 Intrauterine device with retrieval thread Aug 16, 2034 Sebela Womens Hlth
Miudella US10166141 Intrauterine contraceptive device Jun 13, 2034 Sebela Womens Hlth
Miudella US9265652 Intrauterine contraceptive device Apr 28, 2034 Sebela Womens Hlth
Miudella US10022264 Intrauterine device with retrieval thread Mar 22, 2034 Sebela Womens Hlth
Miudella US9180040 Intrauterine Device With Retrieval Thread Mar 22, 2034 Sebela Womens Hlth
Miudella US10398588 Intrauterine device with retrieval thread Feb 24, 2034 Sebela Womens Hlth
Miudella US9610191 Intrauterine device with retrieval thread Feb 24, 2034 Sebela Womens Hlth
Miudella US12138199 Intrauterine device with retrieval thread Oct 18, 2033 Sebela Womens Hlth
Miudella US9089418 Intrauterine contraceptive device Apr 09, 2033 Sebela Womens Hlth
Miudella US10159596 Intrauterine contraceptive device Aug 14, 2032 Sebela Womens Hlth
Miudella US10188546 Intrauterine device with controlled copper ion elution Aug 14, 2032 Sebela Womens Hlth
Miudella US11850181 Intrauterine contraceptive device Aug 14, 2032 Sebela Womens Hlth
Miudella US9427351 Intrauterine contraceptive device Aug 14, 2032 Sebela Womens Hlth



Copper's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Copper:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy M.D. Anderson Cancer Center NA RECRUITING
(Sep 1, 2026)
PHASE1
Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors National Cancer Institute (NCI) NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1
SCRT in TNT With or Without Chlorophyllin Tata Memorial Centre NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE2
Phase 1 Study of Intravaginal KB15A ZabBio Inc. NA RECRUITING
(Sep 1, 2026)
PHASE1
Trientine Tetrahydrochloride Administered Once a Day for the First Line Treatment of Wilson's Disease Patients. Orphalan NA RECRUITING
(Sep 1, 2026)
PHASE3
A Study of the Safety and Efficacy of Prime Editing (PM577) in Participants With Wilson Disease (WD) Prime Medicine, Inc. NA RECRUITING
(Sep 1, 2026)
PHASE1, PHASE2
Oral Zinc Supplementation Combined With Targeted Immunotherapy for Unresectable or Advanced Hepatocellular Carcinoma Anhui Provincial Hospital NA RECRUITING
(Sep 1, 2026)
PHASE2
NanoSALV vs Standard Topical Care Pathway in Sports-Related Skin Lesions Shahab Alizadeh NA NOT YET RECRUITING
(Sep 1, 2026)
PHASE3
A Study of Chlorophyllin or Placebo With Standard Treatment for Late Radiation Induced Luminal Gastrointestinal Tract Bleeding Tata Memorial Centre NA NOT YET RECRUITING
(Sep 1, 2026)
PHASE3
64Cu-DOTA-pembrolizumab PET for the Study of PD1 Expression City of Hope Medical Center NA WITHDRAWN
(Aug 1, 2026)
PHASE1
Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas Case Comprehensive Cancer Center NA RECRUITING
(Aug 1, 2026)
PHASE1
Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer Curium US LLC NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE3
Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study M.D. Anderson Cancer Center NA RECRUITING
(Aug 1, 2026)
PHASE2
A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab City of Hope Medical Center NA RECRUITING
(Aug 1, 2026)
PHASE1
Prevention of Jellyfish Stings University of Minnesota NA COMPLETED
(Jul 1, 2026)
PHASE3
NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease Stephen G. Kaler NA RECRUITING
(Jul 1, 2026)
PHASE1, PHASE2
[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy Brigham and Women's Hospital NA RECRUITING
(Jul 1, 2026)
PHASE3
Chlorophyllin for Reducing Oral Mucositis in Total Body Irradiation Prior to Transplant Tata Memorial Centre NA RECRUITING
(Jul 1, 2026)
PHASE2
The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer Memorial Sloan Kettering Cancer Center NA RECRUITING
(Jun 1, 2026)
PHASE1
Imaging of Solid Tumors Using FAP-2286 Thomas Hope NA RECRUITING
(Jun 1, 2026)
PHASE1
Testing the Addition of An Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Pancreatic Neuroendocrine Tumors National Cancer Institute (NCI) NA ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE1
A Phase 1/2/3 Study of UX701 Gene Therapy in Adults With Wilson Disease Ultragenyx Pharmaceutical Inc NA ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE1, PHASE2
Oral Zn-Telomir Monotherapy in Patients With Advanced or Metastatic Triple-Negative Breast Cancer (TNBC) Telomir Pharmaceuticals, Inc. NA NOT YET RECRUITING
(Jun 1, 2026)
PHASE1, PHASE2
Safety and Diagnostic Performance of uPAR PET Imaging in Localised, Untreated Prostate Cancer Curasight NA RECRUITING
(May 1, 2026)
PHASE2
Effectiveness of MMS Compared With IFS Among Pregnant Women in Bangladesh: an Experimental Study National Institute of Neurosciences and Hospital, Dhaka NA ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE1, PHASE2
NORTHERA (DROXIDOPA) for Dysautonomia in Adult Survivors of Menkes Disease and Occipital Horn Syndrome Stephen G. Kaler, MD NA COMPLETED
(Mar 1, 2026)
PHASE1, PHASE2
Off Treatment Urinary Copper Excretion in Wilson Disease, Pilot Study Yale University NA RECRUITING
(Mar 1, 2026)


Copper Generic API Manufacturers

Given below is the list of companies who have filed for Copper generic, along with the locations of their manufacturing plants worldwide.