Cobicistat Patent Expiration

Cobicistat is Used for treating HIV infection by enhancing the pharmacokinetics and inhibiting cytochrome P450 monooxygenase. It was first introduced by Gilead Sciences Inc in its drug Tybost on Sep 24, 2014. 2 different companies have introduced drugs containing Cobicistat.


Cobicistat Patents

Given below is the list of patents protecting Cobicistat, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Tybost US10039718

(Pediatric)

Use of solid carrier particles to improve the processability of a pharmaceutical agent Apr 06, 2033 Gilead Sciences Inc
Tybost US10039718 Use of solid carrier particles to improve the processability of a pharmaceutical agent Oct 06, 2032 Gilead Sciences Inc
Tybost US8148374

(Pediatric)

Modulators of pharmacokinetic properties of therapeutics Mar 03, 2030 Gilead Sciences Inc
Tybost US8148374 Modulators of pharmacokinetic properties of therapeutics Sep 03, 2029 Gilead Sciences Inc



Cobicistat's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Cobicistat:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation Syndax Pharmaceuticals NA RECRUITING
(Sep 1, 2026)
PHASE1, PHASE2
Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Standard of Care in Virologically Suppressed People With HIV-1 Gilead Sciences NA ACTIVE NOT RECRUITING
(May 1, 2026)
PHASE3
Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV Gilead Sciences NA ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE2, PHASE3
A Study of Teropavimab and Zinlirvimab in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection Gilead Sciences NA ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE2
Estradiol Therapy In Transgender Women to Research Interactions With HIV Therapy National Institute of Allergy and Infectious Diseases (NIAID) NA TERMINATED
(Mar 1, 2026)
PHASE2
A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Participants. Fore Biotherapeutics NA COMPLETED
(Mar 1, 2026)
PHASE1


Cobicistat Generic API Manufacturers

Only one generic application has been filed for Cobicistat.

Given below is the list of companies who have filed for Cobicistat generic, along with the locations of their manufacturing plants worldwide.