Carfilzomib Patent Expiration

Carfilzomib is Used for treating relapsed or refractory multiple myeloma in patients who have received one to three lines of therapy. It was first introduced by Onyx Pharmaceuticals Inc A Wholly Owned Sub Of Amgen Inc in its drug Kyprolis on Jul 20, 2012. 4 different companies have introduced drugs containing Carfilzomib.


Carfilzomib Patents

Given below is the list of patents protecting Carfilzomib, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Kyprolis US9493582 Alkylated cyclodextrin compositions and processes for preparing and using the same Feb 27, 2033 Onyx Pharms Amgen
Kyprolis US9511109 Combination therapy with peptide epoxyketones Oct 21, 2029 Onyx Pharms Amgen
Kyprolis USRE47954 Combination therapy with peptide epoxyketones Oct 21, 2029 Onyx Pharms Amgen
Kyprolis US7737112 Composition for enzyme inhibition Dec 07, 2027 Onyx Pharms Amgen
Kyprolis US7417042 Compounds for enzyme inhibition Jul 20, 2026 Onyx Pharms Amgen
Kyprolis US7232818 Compounds for enzyme inhibition Apr 14, 2025 Onyx Pharms Amgen
Kyprolis US7491704 Compounds for enzyme inhibition Apr 14, 2025 Onyx Pharms Amgen
Kyprolis US8129346 Compounds for enzyme inhibition Apr 14, 2025 Onyx Pharms Amgen
Kyprolis US8207125 Compounds for enzyme inhibition Apr 14, 2025 Onyx Pharms Amgen
Kyprolis US8207126 Compounds for enzyme inhibition Apr 14, 2025 Onyx Pharms Amgen
Kyprolis US8207127 Compounds for enzyme inhibition Apr 14, 2025 Onyx Pharms Amgen
Kyprolis US8207297 Compounds for enzyme inhibition Apr 14, 2025 Onyx Pharms Amgen



Carfilzomib's Family Patents

Family Patents

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Carfilzomib Generic API Manufacturers

Several generic applications have been filed for Carfilzomib. The first generic version for Carfilzomib was by Dr Reddys Laboratories Ltd and was approved on Sep 9, 2019. And the latest generic version is by Breckenridge Pharmaceutical Inc and was approved on Jun 11, 2021.

Given below is the list of companies who have filed for Carfilzomib generic, along with the locations of their manufacturing plants worldwide.


1. APOTEX

Apotex Inc has filed for 2 different strengths of generic version for Carfilzomib. Given below are the details of the strengths of this generic introduced by Apotex.

Strength Dosage Form Availability Application Pathway TE code Launch Date
60MG/VIAL

powder Discontinued INTRAVENOUS N/A Mar 16, 2020
30MG/VIAL

powder Discontinued INTRAVENOUS N/A Mar 20, 2020


Manufacturing Plant Locations
New

Apotex's manufacturing plants are situated in 3 countries - United States, Canada, India. Given below are the details of these plant locations as well as the firm names of Apotex as present at those locations.

Country City Firm Name
United States
Weston Apotex Corp.
Canada
North York Apotex Inc.
Winnipeg Apotex Fermentation Inc.
Etobicoke Apotex, Inc.
Brantford Apotex Pharmachem Inc.
Toronto Apotex Inc.
Richmond Hill Apotex Inc.
India
Bangalore Apotex Pharmachem India Pvt Ltd.
Bengaluru Apotex Research Private Limited
Bangalore Apotex Research Private Limited - Bioequivalence Centre





2. BRECKENRIDGE

Breckenridge Pharmaceutical Inc has filed for 2 different strengths of generic version for Carfilzomib. Given below are the details of the strengths of this generic introduced by Breckenridge.

Strength Dosage Form Availability Application Pathway TE code Launch Date
60MG/VIAL

powder Discontinued INTRAVENOUS N/A Jun 11, 2021
10MG/VIAL

powder Discontinued INTRAVENOUS N/A Jun 11, 2021


Manufacturing Plant Locations
New

Breckenridge's manufacturing plants are situated in 1 country - United States. Given below are the details of these plant locations as well as the firm names of Breckenridge as present at those locations.

Country City Firm Name
United States
Berlin Breckenridge Pharmaceutical, Inc
Boca Raton Breckenridge Pharmaceutical, Inc.





3. DR REDDYS

Dr Reddys Laboratories Ltd has filed for 1 generic for Carfilzomib. Given below are the details of the strengths of this generic introduced by Dr Reddys.

Strength Dosage Form Availability Application Pathway TE code Launch Date
60MG/VIAL

powder Prescription INTRAVENOUS AP Sep 9, 2019