Carfilzomib Patent Expiration

Carfilzomib is Used for treating relapsed or refractory multiple myeloma in patients who have received one to three lines of therapy. It was first introduced by Onyx Pharmaceuticals Inc A Wholly Owned Sub Of Amgen Inc in its drug Kyprolis on Jul 20, 2012. 4 different companies have introduced drugs containing Carfilzomib.


Carfilzomib Patents

Given below is the list of patents protecting Carfilzomib, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Kyprolis US9493582

(Pediatric)

Alkylated cyclodextrin compositions and processes for preparing and using the same Aug 27, 2033 Onyx Pharms Amgen
Kyprolis US9493582 Alkylated cyclodextrin compositions and processes for preparing and using the same Feb 27, 2033 Onyx Pharms Amgen
Kyprolis USRE47954

(Pediatric)

Combination therapy with peptide epoxyketones Apr 21, 2030 Onyx Pharms Amgen
Kyprolis US9511109 Combination therapy with peptide epoxyketones Oct 21, 2029 Onyx Pharms Amgen
Kyprolis USRE47954 Combination therapy with peptide epoxyketones Oct 21, 2029 Onyx Pharms Amgen
Kyprolis US7737112

(Pediatric)

Composition for enzyme inhibition Jun 07, 2028 Onyx Pharms Amgen
Kyprolis US7737112 Composition for enzyme inhibition Dec 07, 2027 Onyx Pharms Amgen
Kyprolis US7417042

(Pediatric)

Compounds for enzyme inhibition Jan 20, 2027 Onyx Pharms Amgen
Kyprolis US7417042 Compounds for enzyme inhibition Jul 20, 2026 Onyx Pharms Amgen
Kyprolis US7232818 Compounds for enzyme inhibition Apr 14, 2025

(Expired)

Onyx Pharms Amgen
Kyprolis US7491704 Compounds for enzyme inhibition Apr 14, 2025

(Expired)

Onyx Pharms Amgen
Kyprolis US8129346 Compounds for enzyme inhibition Apr 14, 2025

(Expired)

Onyx Pharms Amgen
Kyprolis US8207125 Compounds for enzyme inhibition Apr 14, 2025

(Expired)

Onyx Pharms Amgen
Kyprolis US8207126 Compounds for enzyme inhibition Apr 14, 2025

(Expired)

Onyx Pharms Amgen
Kyprolis US8207127 Compounds for enzyme inhibition Apr 14, 2025

(Expired)

Onyx Pharms Amgen
Kyprolis US8207297 Compounds for enzyme inhibition Apr 14, 2025

(Expired)

Onyx Pharms Amgen



Carfilzomib's Family Patents

Family Patents

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Carfilzomib Generic API Manufacturers

Several generic applications have been filed for Carfilzomib. The first generic version for Carfilzomib was by Dr Reddys Laboratories Ltd and was approved on Sep 9, 2019. And the latest generic version is by Breckenridge Pharmaceutical Inc and was approved on Jun 11, 2021.

Given below is the list of companies who have filed for Carfilzomib generic, along with the locations of their manufacturing plants worldwide.