Bupropion Hydrochloride was first introduced by Glaxosmithkline in its drug Wellbutrin on Dec 30, 1985. Other drugs containing Bupropion Hydrochloride are Wellbutrin Sr, Forfivo Xl, Wellbutrin Xl, Zyban. 37 different companies have introduced drugs containing Bupropion Hydrochloride.

Bupropion Hydrochloride Patents

Given below is the list of patents protecting Bupropion Hydrochloride, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in	Drug Patent Number	Drug Patent Title	Drug Patent Expiry	Drug Owner
Forfivo Xl	US7674479	Sustained-release bupropion and bupropion/mecamylamine tablets	Aug 23, 2028	Twi Pharms
Wellbutrin Xl	US6096341	Delayed release tablet of bupropion hydrochloride	Oct 30, 2018 (Expired)	Bausch
Wellbutrin Sr	US5358970	Pharmaceutical composition containing bupropion hydrochloride and a stabilizer	Aug 12, 2013 (Expired)	Glaxosmithkline
Wellbutrin Sr	US5427798	Controlled sustained release tablets containing bupropion	Aug 12, 2013 (Expired)	Glaxosmithkline
Wellbutrin Sr	US5731000	Stabilized pharmaceutical composition containing bupropion	Aug 12, 2013 (Expired)	Glaxosmithkline
Wellbutrin Sr	US5763493	Stabilized pharmaceutical	Aug 12, 2013 (Expired)	Glaxosmithkline
Zyban	US5358970	Pharmaceutical composition containing bupropion hydrochloride and a stabilizer	Aug 12, 2013 (Expired)	Glaxosmithkline
Zyban	US5427798	Controlled sustained release tablets containing bupropion	Aug 12, 2013 (Expired)	Glaxosmithkline
Zyban	US5731000	Stabilized pharmaceutical composition containing bupropion	Aug 12, 2013 (Expired)	Glaxosmithkline
Zyban	US5763493	Stabilized pharmaceutical	Aug 12, 2013 (Expired)	Glaxosmithkline

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Bupropion Hydrochloride's Family Patents

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Bupropion Hydrochloride Generic API Manufacturers

Several generic applications have been filed for Bupropion Hydrochloride. The first generic version for Bupropion Hydrochloride was by Heritage Pharma Labs Inc and was approved on Nov 29, 1999. And the latest generic version is by Ipca Laboratories Ltd and was approved on May 2, 2025.

Given below is the list of companies who have filed for Bupropion Hydrochloride generic, along with the locations of their manufacturing plants worldwide.