Buprenorphine Hydrochloride Patent Expiration

Buprenorphine Hydrochloride is Used for managing severe, long-term pain when other treatments are insufficient, through transmucosal delivery of buprenorphine. It was first introduced by Indivior Inc in its drug Buprenex on Approved Prior to Jan 1, 1982. Other drugs containing Buprenorphine Hydrochloride are Probuphine, Belbuca, Subutex. 16 different companies have introduced drugs containing Buprenorphine Hydrochloride.


Buprenorphine Hydrochloride Patents

Given below is the list of patents protecting Buprenorphine Hydrochloride, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Belbuca US9901539 Transmucosal drug delivery devices for use in chronic pain relief Dec 21, 2032 Bdsi
Belbuca US8147866 Transmucosal delivery devices with enhanced uptake Jul 23, 2027 Bdsi
Belbuca US9655843 Transmucosal delivery devices with enhanced uptake Jul 23, 2027 Bdsi
Probuphine US7736665 Implantable polymeric device for sustained release of buprenorphine Apr 25, 2024

(Expired)

Reacx Pharms
Belbuca US7579019 Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces Jan 22, 2020

(Expired)

Bdsi
Belbuca US6159498 Bioerodable film for delivery of pharmaceutical compounds of mucosal surfaces Oct 18, 2016

(Expired)

Bdsi



Buprenorphine Hydrochloride's Family Patents

Family Patents

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Buprenorphine Hydrochloride Generic API Manufacturers

Several generic applications have been filed for Buprenorphine Hydrochloride. The first generic version for Buprenorphine Hydrochloride was by Hospira Inc and was approved on Jun 3, 1996. And the latest generic version is by Somerset Therapeutics Llc and was approved on Jan 30, 2025.

Given below is the list of companies who have filed for Buprenorphine Hydrochloride generic, along with the locations of their manufacturing plants worldwide.