Atovaquone Patent Expiration

Atovaquone is Used for treating Pneumocystis carinii infections. It was first introduced by Glaxosmithkline Llc in its drug Mepron on Nov 25, 1992. 10 different companies have introduced drugs containing Atovaquone.


Atovaquone Patents

Given below is the list of patents protecting Atovaquone, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Mepron US6649659

(Pediatric)

Atovaquone pharmaceutical compositions Jan 10, 2017

(Expired)

Glaxosmithkline Llc
Mepron US6649659 Atovaquone pharmaceutical compositions Jul 10, 2016

(Expired)

Glaxosmithkline Llc



Atovaquone's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Atovaquone:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
Atovaquone Combined With Radiation in Children With Malignant Brain Tumors Emory University NA RECRUITING
(Jul 1, 2026)
PHASE1
Safety, Tolerability and Efficacy of PfSPZ-LARC2 Vaccine Against CHMI in Malaria-Naïve Adults Sanaria Inc. NA RECRUITING
(Jun 1, 2026)
PHASE1
Safety and PK of MMV371 LAI in Healthy Adults and Adolescents in Rwanda Medicines for Malaria Venture NA NOT YET RECRUITING
(Apr 1, 2026)
PHASE1


Atovaquone Generic API Manufacturers

Several generic applications have been filed for Atovaquone. The first generic version for Atovaquone was by Amneal Pharmaceuticals and was approved on Mar 18, 2014. And the latest generic version is by Pai Holdings Llc Dba Pharmaceutical Associates Inc And Dba Pai Pharma and was approved on Oct 25, 2021.

Given below is the list of companies who have filed for Atovaquone generic, along with the locations of their manufacturing plants worldwide.