Arsenic Trioxide Patent Expiration

Arsenic Trioxide is Used for treating acute promyelocytic leukemia (APL) characterized by specific genetic markers and resistance to traditional chemotherapy. It was first introduced by Cephalon Inc in its drug Trisenox on Sep 25, 2000. 12 different companies have introduced drugs containing Arsenic Trioxide.


Arsenic Trioxide Patents

Given below is the list of patents protecting Arsenic Trioxide, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Trisenox US6723351 Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol Nov 10, 2018

(Expired)

Cephalon
Trisenox US6855339 Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol Nov 10, 2018

(Expired)

Cephalon
Trisenox US6861076 Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol Nov 10, 2018

(Expired)

Cephalon
Trisenox US6884439 Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol Nov 10, 2018

(Expired)

Cephalon
Trisenox US6982096 Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol Nov 10, 2018

(Expired)

Cephalon
Trisenox US8273379 Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol Nov 10, 2018

(Expired)

Cephalon



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Arsenic Trioxide's patents.

Given below is the list recent legal activities going on the following patents of Arsenic Trioxide.

Activity Date Patent Number
Patent litigations
Expire Patent 02 Nov, 2020 US8273379
Maintenance Fee Reminder Mailed 18 May, 2020 US8273379
Patent Issue Date Used in PTA Calculation 25 Sep, 2012 US8273379
Recordation of Patent Grant Mailed 25 Sep, 2012 US8273379
Email Notification 06 Sep, 2012 US8273379
Issue Notification Mailed 05 Sep, 2012 US8273379
Dispatch to FDC 29 Aug, 2012 US8273379
Application Is Considered Ready for Issue 28 Aug, 2012 US8273379
Issue Fee Payment Received 27 Aug, 2012 US8273379
Issue Fee Payment Verified 27 Aug, 2012 US8273379


Arsenic Trioxide's Family Patents

Family Patents

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Arsenic Trioxide Generic API Manufacturers

Several generic applications have been filed for Arsenic Trioxide. The first generic version for Arsenic Trioxide was by Fresenius Kabi Usa Llc and was approved on Aug 31, 2018. And the latest generic version is by Orbicular Pharmaceutical Technologies Private Ltd and was approved on Apr 20, 2023.

Given below is the list of companies who have filed for Arsenic Trioxide generic, along with the locations of their manufacturing plants worldwide.