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Apixaban Patent Expiration

Apixaban is Used for reducing the risk of stroke and systemic embolism. It was first introduced by Bristol Myers Squibb Co Pharmaceutical Research Institute in its drug Eliquis on Dec 28, 2012. Another drug containing Apixaban is Eliquis Sprinkle. 15 different companies have introduced drugs containing Apixaban.


Apixaban Patents

Given below is the list of patents protecting Apixaban, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Eliquis Sprinkle US11896586

(Pediatric)

 Apixaban formulations May 22, 2041 Bristol
Eliquis Sprinkle US11896586 Apixaban formulations Nov 22, 2040 Bristol
Eliquis US9326945

(Pediatric)

 Apixaban formulations Aug 24, 2031 Bristol Myers Squibb
Eliquis US9326945 Apixaban formulations Feb 24, 2031 Bristol Myers Squibb
Eliquis US6967208

(Pediatric)

 Lactam-containing compounds and derivatives thereof as factor Xa inhibitors May 21, 2027 Bristol Myers Squibb
Eliquis Sprinkle US6967208

(Pediatric)

 Lactam-containing compounds and derivatives thereof as factor Xa inhibitors May 21, 2027 Bristol
Eliquis US6967208 Lactam-containing compounds and derivatives thereof as factor Xa inhibitors Nov 21, 2026 Bristol Myers Squibb
Eliquis Sprinkle US6967208 Lactam-containing compounds and derivatives thereof as factor Xa inhibitors Nov 21, 2026 Bristol
Eliquis US6413980 Nitrogen containing heterobicycles as factor Xa inhibitors Dec 22, 2019

(Expired)

 Bristol Myers Squibb



Apixaban's Family Patents

Family Patents

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Apixaban Generic API Manufacturers

Several generic applications have been filed for Apixaban. The first generic version for Apixaban was by Mylan Pharmaceuticals Inc and was approved on Dec 23, 2019. And the latest generic version is by Macleods Pharmaceuticals Ltd and was approved on Feb 27, 2025.

Given below is the list of companies who have filed for Apixaban generic, along with the locations of their manufacturing plants worldwide.


1. ACCORD HLTHCARE

Accord Healthcare Inc has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Accord Hlthcare.

Strength Dosage Form Availability Application Pathway TE code Launch Date
5MG

tablet Prescription ORAL AB Jul 28, 2020
2.5MG

tablet Prescription ORAL AB Jul 28, 2020





2. APOTEX

Apotex Inc has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Apotex.

Strength Dosage Form Availability Application Pathway TE code Launch Date
2.5MG

tablet Discontinued ORAL N/A Feb 16, 2024
5MG

tablet Discontinued ORAL N/A Feb 16, 2024


Manufacturing Plant Locations
New

Apotex's manufacturing plants are situated in 3 countries - United States, Canada, India. Given below are the details of these plant locations as well as the firm names of Apotex as present at those locations.

Country City Firm Name
United States
Weston Apotex Corp.
Canada
North York Apotex Inc.
Brantford Apotex Pharmachem Inc.
Toronto Apotex Inc.
Richmond Hill Apotex Inc.
Etobicoke Apotex, Inc.
Winnipeg Apotex Fermentation Inc.
India
Bangalore Apotex Research Private Limited - Bioequivalence Centre
Bangalore Apotex Pharmachem India Pvt Ltd.
Bengaluru Apotex Research Private Limited





3. AUROBINDO PHARMA LTD

Aurobindo Pharma Ltd has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Aurobindo Pharma Ltd.

Strength Dosage Form Availability Application Pathway TE code Launch Date
5MG

tablet Discontinued ORAL N/A May 26, 2023
2.5MG

tablet Discontinued ORAL N/A May 26, 2023


Manufacturing Plant Locations
New

Aurobindo Pharma Ltd's manufacturing plants are situated in 1 country - India. Given below are the details of these plant locations as well as the firm names of Aurobindo Pharma Ltd as present at those locations.

Country City Firm Name
India
Medchal Aurobindo Pharma Ltd





4. BIONPHARMA

Bionpharma Inc has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Bionpharma.

Strength Dosage Form Availability Application Pathway TE code Launch Date
5MG

tablet Discontinued ORAL N/A Apr 8, 2020
2.5MG

tablet Discontinued ORAL N/A Apr 8, 2020


Manufacturing Plant Locations
New

Bionpharma's manufacturing plants are situated in 1 country - United States. Given below are the details of these plant locations as well as the firm names of Bionpharma as present at those locations.

Country City Firm Name
United States
Princeton Bionpharma Inc.





5. BRECKENRIDGE

Breckenridge Pharmaceutical Inc has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Breckenridge.

Strength Dosage Form Availability Application Pathway TE code Launch Date
2.5MG

tablet Discontinued ORAL N/A Jul 26, 2021
5MG

tablet Discontinued ORAL N/A Jul 26, 2021


Manufacturing Plant Locations
New

Breckenridge's manufacturing plants are situated in 1 country - United States. Given below are the details of these plant locations as well as the firm names of Breckenridge as present at those locations.

Country City Firm Name
United States
Berlin Breckenridge Pharmaceutical, Inc
Boca Raton Breckenridge Pharmaceutical, Inc.





6. HETERO LABS LTD V

Hetero Labs Ltd Unit V has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Hetero Labs Ltd V.

Strength Dosage Form Availability Application Pathway TE code Launch Date
5MG

tablet Discontinued ORAL N/A Nov 21, 2023
2.5MG

tablet Discontinued ORAL N/A Nov 21, 2023





7. IMPAX

Impax Laboratories Llc has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Impax.

Strength Dosage Form Availability Application Pathway TE code Launch Date
5MG

tablet Prescription ORAL AB Feb 14, 2025
2.5MG

tablet Prescription ORAL AB Feb 14, 2025


Manufacturing Plant Locations
New

Impax's manufacturing plants are situated in 1 country - United States. Given below are the details of these plant locations as well as the firm names of Impax as present at those locations.

Country City Firm Name
United States
Hayward Impax Laboratories, LLC.





8. INDOCO

Indoco Remedies Ltd has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Indoco.

Strength Dosage Form Availability Application Pathway TE code Launch Date
2.5MG

tablet Prescription ORAL AB Sep 11, 2020
5MG

tablet Prescription ORAL AB Sep 11, 2020


Manufacturing Plant Locations
New

Indoco's manufacturing plants are situated in 1 country - India. Given below are the details of these plant locations as well as the firm names of Indoco as present at those locations.

Country City Firm Name
India
Verna Indoco Remedies Limited (Plant I)
Verna Indoco Remedies Limited
Taluka Khalapur, District Raigad Indoco Remedies Limited
Navi Mumbai Indoco Remedies Limited





9. MACLEODS PHARMS LTD

Macleods Pharmaceuticals Ltd has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Macleods Pharms Ltd.

Strength Dosage Form Availability Application Pathway TE code Launch Date
2.5MG

tablet Prescription ORAL AB Feb 27, 2025
5MG

tablet Prescription ORAL AB Feb 27, 2025





10. MICRO LABS

Micro Labs Ltd has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Micro Labs.

Strength Dosage Form Availability Application Pathway TE code Launch Date
5MG

tablet Discontinued ORAL N/A Dec 23, 2019
2.5MG

tablet Discontinued ORAL N/A Dec 23, 2019


Manufacturing Plant Locations
New

Micro Labs's manufacturing plants are situated in 1 country - India. Given below are the details of these plant locations as well as the firm names of Micro Labs as present at those locations.

Country City Firm Name
India
Verna Micro Labs Limited
Bangalore Micro Labs Limited
Bengaluru Micro Labs Limited
Bengaluru Micro Labs Limited, Central Analytical Laboratory





11. MYLAN

Mylan Pharmaceuticals Inc has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Mylan.

Strength Dosage Form Availability Application Pathway TE code Launch Date
2.5MG

tablet Discontinued ORAL N/A Dec 23, 2019
5MG

tablet Discontinued ORAL N/A Dec 23, 2019


Manufacturing Plant Locations
New

Mylan's manufacturing plants are situated in 4 countries - United States, India, Canada, Ireland. Given below are the details of these plant locations as well as the firm names of Mylan as present at those locations.

Country City Firm Name
United States
Morgantown MYLAN CONSUMER HEALTHCARE Inc.
Morgantown Mylan Specialty, L.P.
Santa Barbara Mylandon LLC dba Debbie s Delights Santa Barbara Baking Co.
Saint Albans Mylan Technologies, Inc.
San Carlos Mylan Pharmaceuticals Inc.
Rockford Mylan Institutional, Inc.
Greensboro Mylan Pharmaceuticals Inc
India
Anekal Taluk, Bangalore Mylan Laboratories Limited
Pithampur, District Dhar Mylan Laboratories Limited
Hyderabad Mylan Laboratories Limited
Hosur Mylan Laboratories Limited
Aurangabad Mylan Laboratories Limited (FDF-2)
Sinnar Mylan Laboratories Limited
Sarigam Mylan Laboratories Limited
Bangalore Mylan Laboratories Limited
Canada
Etobicoke Mylan Pharmaceuticals ULC
Ireland
Inverin Mylan Teoranta





12. TORRENT

Torrent Pharmaceuticals Ltd has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Torrent.

Strength Dosage Form Availability Application Pathway TE code Launch Date
2.5MG

tablet Prescription ORAL AB Dec 17, 2024
5MG

tablet Prescription ORAL AB Dec 17, 2024


Manufacturing Plant Locations
New

Torrent's manufacturing plants are situated in 2 countries - India, United States. Given below are the details of these plant locations as well as the firm names of Torrent as present at those locations.

Country City Firm Name
India
Gandhi Nagar Torrent Pharmaceuticals Limited
Bharuch Torrent Pharmaceuticals Limited
Pithampur Torrent Pharmaceuticals Limited
Thanam Torrent Pharmaceuticals Limited
Indrad Torrent Pharmaceuticals Limited
United States
Kalamazoo Torrent Pharma Inc.
Basking Ridge Torrent Pharma Inc.





13. ZYDUS PHARMS

Zydus Pharmaceuticals Usa Inc has filed for 2 different strengths of generic version for Apixaban. Given below are the details of the strengths of this generic introduced by Zydus Pharms.

Strength Dosage Form Availability Application Pathway TE code Launch Date
2.5MG

tablet Discontinued ORAL N/A Feb 27, 2023
5MG

tablet Discontinued ORAL N/A Feb 27, 2023





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