Alprazolam Patent Expiration

Alprazolam was first introduced by Upjohn Us 2 Llc in its drug Xanax on Approved Prior to Jan 1, 1982. Other drugs containing Alprazolam are Xanax Xr, Niravam. 27 different companies have introduced drugs containing Alprazolam.


Alprazolam Patents

Given below is the list of patents protecting Alprazolam, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Niravam US6024981 Rapidly dissolving robust dosage form Apr 09, 2018

(Expired)

Ucb Inc
Niravam US6221392 Rapidly dissolving robust dosage form Apr 09, 2018

(Expired)

Ucb Inc



Alprazolam's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Alprazolam:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures UCB Biopharma SRL NA RECRUITING
(Sep 1, 2026)
PHASE3
A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures UCB Biopharma SRL NA ENROLLING BY INVITATION
(Aug 1, 2026)
PHASE3
A Study of Soticlestat in Healthy Adult Nondependent Recreational Drug Users With Central Nervous System (CNS) Depressant Experience Takeda NA COMPLETED
(Aug 1, 2026)
PHASE1
Identification of a Safe and Non-Psychedelic Dose of Psilocybin Diamond Therapeutics Inc. NA COMPLETED
(Jul 1, 2026)
PHASE1
Opioid Drug Interaction Study Shanna Babalonis, PhD NA RECRUITING
(May 1, 2026)
PHASE1, PHASE2
Staccato Alprazolam and Photoparoxysmal Response Nova Pneuma Inc. NA COMPLETED
(Apr 1, 2026)
PHASE2
Motor and Non-Motor Effects of Low-Intensity Focused Ultrasound (LIFU) as a Neuromodulation Tool in Essential Tremor University of Sao Paulo General Hospital NA NOT YET RECRUITING
(Mar 1, 2026)
PHASE1, PHASE2


Alprazolam Generic API Manufacturers

Several generic applications have been filed for Alprazolam. The first generic version for Alprazolam was by Novitium Pharma Llc and was approved on Oct 19, 1993. And the latest generic version is by Unichem Laboratories Ltd and was approved on Jul 13, 2026.

Given below is the list of companies who have filed for Alprazolam generic, along with the locations of their manufacturing plants worldwide.


Alprazolam News

Delhi Police's ANTF Dismantles Inter-State Drug Syndicate; Seizes Alprazolam and Tramadol Valued at 4.5 Crore

29 Mar, 2026

DRI conducts a raid on an unlawful Alprazolam manufacturing facility in Andhra Pradesh, seizing 237 kg of drugs and more than 3.5 tonnes of...

13 Mar, 2026

Numerous drug raids and confiscations of illegal substances in Haryana, Chhattisgarh, and Uttarakhand.

26 Feb, 2026

Numerous individuals taken into custody as authorities confiscate crores of diverted codeine syrup in multiple states.

15 Feb, 2026

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