Adapalene is Used for treating acne vulgaris. It was first introduced by Galderma Laboratories Lp in its drug Differin on May 31, 1996. 10 different companies have introduced drugs containing Adapalene.

Adapalene Patents

Given below is the list of patents protecting Adapalene, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in	Drug Patent Number	Drug Patent Title	Drug Patent Expiry	Drug Owner
Differin	US7998467	Cosmetic/dermatological compositions comprising naphthoic acid compounds and polyurethane polymers	May 31, 2028	Galderma Labs Lp
Differin	US8435502	Cosmetic/dermatological compositions comprising naphtholic acid compounds and polyurethane polymers	Sep 15, 2026	Galderma Labs Lp
Differin	US8709392	Cosmetic/dermatological compositions comprising naphthoic acid compounds and polyurethane polymers	Sep 15, 2026	Galderma Labs Lp
Differin	US7579377	Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders	Feb 23, 2025 (Expired)	Galderma Labs Lp
Differin	US7737181	Pharmaceutical compositions comprising 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders	Aug 29, 2024 (Expired)	Galderma Labs Lp
Differin	US7834060	Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphtoic acid for the treatment of dermatological disorders	Mar 12, 2023 (Expired)	Galderma Labs Lp
Differin	US7838558	Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders	Mar 12, 2023 (Expired)	Galderma Labs Lp
Differin	US7868044	Method for the treatment of acne using compositions comprising 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid	Mar 12, 2023 (Expired)	Galderma Labs Lp
Differin	US8703820	Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders	Mar 12, 2023 (Expired)	Galderma Labs Lp

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Adapalene's Family Patents

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Adapalene Generic API Manufacturers

Several generic applications have been filed for Adapalene. The first generic version for Adapalene was by P And L Development Llc and was approved on Jun 2, 2010. And the latest generic version is by Taro Pharmaceuticals Inc and was approved on Jan 14, 2022.

Given below is the list of companies who have filed for Adapalene generic, along with the locations of their manufacturing plants worldwide.