List of Aklief drug patents

Aklief is owned by Galderma Labs Lp.

Aklief contains Trifarotene.

Aklief has a total of 5 drug patents out of which 0 drug patents have expired.

Aklief was authorised for market use on 04 October, 2019.

Aklief is available in cream;topical dosage forms.

Aklief can be used as treatment of acne vulgaris, method of activating rargamma receptor, topical treatment of acne vulgaris.

Drug patent challenges can be filed against Aklief from 2023-10-05.

The generics of Aklief are possible to be released after 30 May, 2033.

AKLIEF's oppositions filed in EPO
Patent Number Company Patent Title Patent Expiry Activity Alert
These patents protects the active chemical substance. Only patent owner can launch products that use this active substance.
US7807708 GALDERMA LABS LP Ligands that modulate RAR receptors and pharmaceutical/cosmetic compositions comprised thereof
Oct, 2026

(3 years from now)

These patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US8470871 GALDERMA LABS LP Ligands that modulate RAR receptors
Dec, 2025

(2 years from now)

US8227507 GALDERMA LABS LP Ligands that modulate RAR receptors
Dec, 2025

(2 years from now)

US9084778 GALDERMA LABS LP Topical compositions containing a retinoid of the oil-in-water emulsion type
May, 2033

(10 years from now)

US9498465 GALDERMA LABS LP Topical compositions in the form of a gel containing a particular solubilized retinoid
May, 2033

(10 years from now)

Exclusivity Exclusivity Expiration
New Chemical Entity Exclusivity (NCE) Oct 4, 2024

Drugs and Companies using TRIFAROTENE ingredient

NCE-1 date: 2023-10-05

Market Authorisation Date: 04 October, 2019

Treatment: Method of activating rargamma receptor; Topical treatment of acne vulgaris; Treatment of acne vulgaris

Dosage: CREAM;TOPICAL

More Information on Dosage

AKLIEF family patents

8

United States

6

European Union

3

France

3

Mexico

3

Australia

3

Russia

3

Brazil

3

Korea, Republic of

3

China

3

Japan

3

Canada

2

South Africa

2

Spain

1

Israel

1

Denmark

1

Austria

1

Hong Kong

1

Slovenia

1

Lithuania

1

Hungary

1

Singapore

1

Argentina

1

Portugal

1

Cyprus

1

Netherlands

1

Poland

1

Chile

1

New Zealand

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