Vertex Pharms Drug Patent Portfolio

Vertex Pharms owns 2 orange book drugs protected by 12 US patents Given below is the list of Vertex Pharms's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10646481 Pharmaceutical composition and administrations thereof 13 Aug, 2029
Active
US11564916 Pharmaceutical composition and administrations thereof 13 Aug, 2029
Active
US8431615 Dose forms 30 May, 2028
Active
US8324242 Modulators of ATP-binding cassette transporters 05 Aug, 2027
Active
US7495103 Modulators of ATP-binding cassette transporters 20 May, 2027
Active
US8410274 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide 28 Dec, 2026
Active
US8754224 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide 28 Dec, 2026
Active
US9670163 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide 28 Dec, 2026
Active
US8354427 Modulators of ATP-binding cassette transporters 06 Jul, 2026
Active
US8629162 Modulators of ATP-binding cassette transporters 24 Jun, 2025
Active
US7820671 Peptidomimetic protease inhibitors 25 Feb, 2025
Active
US8529882 Peptidomimetic protease inhibitors 31 Aug, 2021 Expired


Given below is the list of recent legal activities going on the following drug patents of Vertex Pharms.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 12th Year, Large Entity 15 Jul, 2024 US8354427
Payment of Maintenance Fee, 12th Year, Large Entity 04 Jun, 2024 US8324242 (Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 13 Nov, 2023 US10646481
Recordation of Patent Grant Mailed 12 Sep, 2023 US11752106
Mail Patent eGrant Notification 12 Sep, 2023 US11752106
Email Notification 12 Sep, 2023 US11752106
Patent Issue Date Used in PTA Calculation 12 Sep, 2023 US11752106
Patent eGrant Notification 12 Sep, 2023 US11752106
Recordation of Patent eGrant 12 Sep, 2023 US11752106
Email Notification 24 Aug, 2023 US11752106
Issue Notification Mailed 23 Aug, 2023 US11752106
Dispatch to FDC 04 Aug, 2023 US11752106
Application Is Considered Ready for Issue 04 Aug, 2023 US11752106
Issue Fee Payment Received 20 Jul, 2023 US11752106
Issue Fee Payment Verified 20 Jul, 2023 US11752106


Vertex Pharms Drug Patents' Oppositions Filed in EPO

Vertex Pharms drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Nov 03, 2017, by Georg Kalhammer/Stephan Teipel. This opposition was filed on patent number EP06848237A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP17204189A Sep, 2021 STADA Arzneimittel AG Granted and Under Opposition
EP17204189A Sep, 2021 Lederer & Keller Patentanwälte Partnerschaft mbB Granted and Under Opposition
EP17204189A Sep, 2021 Teva Pharmaceutical Industries Ltd Granted and Under Opposition
EP10708442A Oct, 2019 Teva Pharmaceutical Industries Ltd Granted and Under Opposition
EP06848237A Nov, 2017 Georg Kalhammer/Stephan Teipel Opposition rejected


Vertex Pharms's Family Patents

Vertex Pharms drugs have patent protection in a total of 43 countries. It's US patent count contributes only to 18.6% of its total global patent coverage. 13 countries have all of their patents expired or invalidated which has opened up potential generic launch opportunities in these countries. Click below to unlock the full patent family tree.

Family Patents



Vertex Pharms Drug List

Given below is the complete list of Vertex Pharms's drugs and the patents protecting them.


1. Incivek

Incivek is protected by 3 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8431615 Dose forms 30 May, 2028
(3 years from now)
Active
US7820671 Peptidomimetic protease inhibitors 25 Feb, 2025
(4 months from now)
Active
US8529882 Peptidomimetic protease inhibitors 31 Aug, 2021
(3 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Incivek's drug page


2. Kalydeco

Kalydeco is protected by 9 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10646481 Pharmaceutical composition and administrations thereof 13 Aug, 2029
(4 years from now)
Active
US11564916 Pharmaceutical composition and administrations thereof 13 Aug, 2029
(4 years from now)
Active
US8324242 Modulators of ATP-binding cassette transporters 05 Aug, 2027
(2 years from now)
Active
US7495103 Modulators of ATP-binding cassette transporters 20 May, 2027
(2 years from now)
Active
US8410274 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide 28 Dec, 2026
(2 years from now)
Active
US8754224 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide 28 Dec, 2026
(2 years from now)
Active
US9670163 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide 28 Dec, 2026
(2 years from now)
Active
US8354427 Modulators of ATP-binding cassette transporters 06 Jul, 2026
(1 year, 8 months from now)
Active
US8629162 Modulators of ATP-binding cassette transporters 24 Jun, 2025
(8 months from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Kalydeco's drug page


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