Pharmacyclics Llc Drug Patent Portfolio

Pharmacyclics Llc owns 1 orange book drug protected by 81 US patents Given below is the list of Pharmacyclics Llc's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10010507 Pharmaceutical formulations of a bruton's tyrosine kinase inhibitor 03 Sep, 2036
Active
US10213386 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Sep, 2036
Active
US10828259 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Sep, 2036
Active
US9655857 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Sep, 2036
Active
US10010507 Pharmaceutical formulations of a bruton's tyrosine kinase inhibitor 03 Mar, 2036
Active
US10213386 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Mar, 2036
Active
US10828259 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Mar, 2036
Active
US9655857 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Mar, 2036
Active
US10463668 Methods of treating and preventing graft versus host disease 24 Apr, 2035
Active
US10695350 Methods of treating and preventing graft versus host disease 24 Apr, 2035
Active
US9795604 Methods of treating and preventing graft versus host disease 24 Apr, 2035
Active
US10463668 Methods of treating and preventing graft versus host disease 24 Oct, 2034
Active
US10695350 Methods of treating and preventing graft versus host disease 24 Oct, 2034
Active
US9795604 Methods of treating and preventing graft versus host disease 24 Oct, 2034
Active
US9296753 Crystalline forms of a Bruton's tyrosine kinase inhibitor 30 Apr, 2034
Active
US9540382 Crystalline forms of a Bruton's tyrosine kinase inhibitor 18 Feb, 2034
Active
US10106548 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
Active
US10125140 Crystalline forms of a bruton's tyrosine kinase inhibitor 03 Dec, 2033
Active
US10294231 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
Active
US10294232 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
Active
US10752634 Crystalline forms of a brutons tyrosine kinase inhibitor 03 Dec, 2033
Active
US10961251 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
Active
US9713617 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
Active
US9725455 Crystalline forms of a bruton's tyrosine kinase inhibitor 03 Dec, 2033
Active
US9296753 Crystalline forms of a Bruton's tyrosine kinase inhibitor 30 Oct, 2033
Active
US9540382 Crystalline forms of a Bruton's tyrosine kinase inhibitor 18 Aug, 2033
Active
US10106548 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
Active
US10125140 Crystalline forms of a bruton's tyrosine kinase inhibitor 03 Jun, 2033
Active
US10294231 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
Active
US10294232 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
Active
US10752634 Crystalline forms of a brutons tyrosine kinase inhibitor 03 Jun, 2033
Active
US10961251 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
Active
US9713617 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
Active
US9725455 Crystalline forms of a bruton's tyrosine kinase inhibitor 03 Jun, 2033
Active
US10004746 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
Active
US10016435 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
Active
US10478439 Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Dec, 2031
Active
US10653696 Use of inhibitors of bruton's tyrosine kinase (BTK) 03 Dec, 2031
Active
US10751342 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
Active
US8754090 Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Dec, 2031
Active
US8999999 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
Active
US9125889 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
Active
US9801881 Use of inhibitors of bruton's tyrosine kinase (BTK) 03 Dec, 2031
Active
US9801883 Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Dec, 2031
Active
US9814721 Use of inhibitors of bruton'S tyrosine kinase (BTK) 03 Dec, 2031
Active
US10004746 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
Active
US10016435 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
Active
US10478439 Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Jun, 2031
Active
US10653696 Use of inhibitors of bruton's tyrosine kinase (BTK) 03 Jun, 2031
Active
US10751342 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
Active
US11672803 Use of inhibitors of Brutons tyrosine kinase (Btk) 03 Jun, 2031
Active
US8754090 Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Jun, 2031
Active
US8999999 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
Active
US9125889 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
Active
US9801881 Use of inhibitors of bruton's tyrosine kinase (BTK) 03 Jun, 2031
Active
US9801883 Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Jun, 2031
Active
US9814721 Use of inhibitors of bruton'S tyrosine kinase (BTK) 03 Jun, 2031
Active
US8008309 Inhibitors of bruton's tyrosine kinase 13 May, 2028
Active
US8008309 Inhibitors of bruton's tyrosine kinase 13 Nov, 2027
Active
US8563563 Inhibitors of bruton's tyrosine kinase 26 Oct, 2027
Active
US7514444 Inhibitors of bruton's tyrosine kinase 28 Jun, 2027
Active
US8476284 Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
Active
US8497277 Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
Active
US8697711 Inhibitors of bruton'S tyrosine kinase 28 Jun, 2027
Active
US8703780 Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
Active
US8735403 Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
Active
US8754091 Inhibitors of bruton's tyrosine kinase 28 Jun, 2027
Active
US8952015 Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
Active
US8957079 Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
Active
US9181257 Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
Active
US8563563 Inhibitors of bruton's tyrosine kinase 26 Apr, 2027
Active
US7514444 Inhibitors of bruton's tyrosine kinase 28 Dec, 2026
Active
US8476284 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
Active
US8497277 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
Active
US8697711 Inhibitors of bruton'S tyrosine kinase 28 Dec, 2026
Active
US8703780 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
Active
US8735403 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
Active
US8754091 Inhibitors of bruton's tyrosine kinase 28 Dec, 2026
Active
US8952015 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
Active
US8957079 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
Active
US9181257 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
Active


Given below is the list of recent legal activities going on the following drug patents of Pharmacyclics Llc.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 8th Year, Large Entity 13 Jun, 2024 US9540382
Request for Trial Granted 01 May, 2024 US11672803 (Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 11 Apr, 2024 US10828259
Payment of Maintenance Fee, 4th Year, Large Entity 11 Jan, 2024 US10751342 (Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 11 Jan, 2024 US10752634
Letter from FDA or Dept of Agriculture re PTE application 18 Dec, 2023 US8008309
Payment of Maintenance Fee, 4th Year, Large Entity 10 Nov, 2023 US10695350
Petition Requesting Trial 06 Nov, 2023 US11672803 (Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 12 Oct, 2023 US10653696 (Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 10 Aug, 2023 US9296753
Patent eGrant Notification 13 Jun, 2023 US11672803 (Litigated)
Recordation of Patent eGrant 13 Jun, 2023 US11672803 (Litigated)
Sequence Moved to Public Database 13 Jun, 2023 US11672803 (Litigated)
Mail Patent eGrant Notification 13 Jun, 2023 US11672803 (Litigated)
Email Notification 13 Jun, 2023 US11672803 (Litigated)


Pharmacyclics Llc's Drug Patent Litigations

Pharmacyclics Llc's drugs have been subject to various legal proceedings, including patent litigations. The earliest legal proceeding was initiated on Apr 20, 2015, against patent number US8754090. The petitioner Coalition for Affordable Drugs IV LLC, challenged the validity of this patent, with Pharmacyclics, Inc. as the respondent. Click below to track the latest information on how companies are challenging Pharmacyclics Llc's patents.

Patent Proceeding Filing Date Status Respondent Petitioner
Patent litigations
US11672803 November, 2023 Trial Instituted
(01 May, 2024)
Pharmacyclics LLC BeiGene USA, Inc. et al.
US9795604 March, 2019 Final Written Decision
(24 Sep, 2020)
Pharmacyclics LLC et al. Sandoz Inc. et al.
US8754090 April, 2015 Terminated-Denied
(19 Oct, 2015)
Pharmacyclics, Inc. Coalition for Affordable Drugs IV LLC


Pharmacyclics Llc Drug Patents' Oppositions Filed in EPO

Pharmacyclics Llc drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Oct 17, 2018, by Generics (U.K.) Limited. This opposition was filed on patent number EP12166302A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP12166302A Oct, 2018 Generics (U.K.) Limited Revoked


Pharmacyclics Llc's Family Patents

Pharmacyclics Llc drugs have patent protection in a total of 43 countries. It's US patent count contributes only to 35.1% of its total global patent coverage. 3 countries have all of their patents expired or invalidated which has opened up potential generic launch opportunities in these countries. Click below to unlock the full patent family tree.

Family Patents



Pharmacyclics Llc Drug List

Given below is the complete list of Pharmacyclics Llc's drugs and the patents protecting them.


1. Imbruvica

Imbruvica is protected by 81 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10010507
(Pediatric)
Pharmaceutical formulations of a bruton's tyrosine kinase inhibitor 03 Sep, 2036
(11 years from now)
Active
US10213386
(Pediatric)
Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Sep, 2036
(11 years from now)
Active
US10828259
(Pediatric)
Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Sep, 2036
(11 years from now)
Active
US9655857
(Pediatric)
Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Sep, 2036
(11 years from now)
Active
US10010507 Pharmaceutical formulations of a bruton's tyrosine kinase inhibitor 03 Mar, 2036
(11 years from now)
Active
US10213386 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Mar, 2036
(11 years from now)
Active
US10828259 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Mar, 2036
(11 years from now)
Active
US9655857 Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor 03 Mar, 2036
(11 years from now)
Active
US10463668
(Pediatric)
Methods of treating and preventing graft versus host disease 24 Apr, 2035
(10 years from now)
Active
US10695350
(Pediatric)
Methods of treating and preventing graft versus host disease 24 Apr, 2035
(10 years from now)
Active
US9795604
(Pediatric)
Methods of treating and preventing graft versus host disease 24 Apr, 2035
(10 years from now)
Active
US10463668 Methods of treating and preventing graft versus host disease 24 Oct, 2034
(9 years from now)
Active
US10695350 Methods of treating and preventing graft versus host disease 24 Oct, 2034
(9 years from now)
Active
US9795604 Methods of treating and preventing graft versus host disease 24 Oct, 2034
(9 years from now)
Active
US9296753
(Pediatric)
Crystalline forms of a Bruton's tyrosine kinase inhibitor 30 Apr, 2034
(9 years from now)
Active
US9540382
(Pediatric)
Crystalline forms of a Bruton's tyrosine kinase inhibitor 18 Feb, 2034
(9 years from now)
Active
US10106548
(Pediatric)
Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
(9 years from now)
Active
US10125140
(Pediatric)
Crystalline forms of a bruton's tyrosine kinase inhibitor 03 Dec, 2033
(9 years from now)
Active
US10294231
(Pediatric)
Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
(9 years from now)
Active
US10294232
(Pediatric)
Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
(9 years from now)
Active
US10752634
(Pediatric)
Crystalline forms of a brutons tyrosine kinase inhibitor 03 Dec, 2033
(9 years from now)
Active
US10961251
(Pediatric)
Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
(9 years from now)
Active
US9713617
(Pediatric)
Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Dec, 2033
(9 years from now)
Active
US9725455
(Pediatric)
Crystalline forms of a bruton's tyrosine kinase inhibitor 03 Dec, 2033
(9 years from now)
Active
US9296753 Crystalline forms of a Bruton's tyrosine kinase inhibitor 30 Oct, 2033
(8 years from now)
Active
US9540382 Crystalline forms of a Bruton's tyrosine kinase inhibitor 18 Aug, 2033
(8 years from now)
Active
US10106548 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
(8 years from now)
Active
US10125140 Crystalline forms of a bruton's tyrosine kinase inhibitor 03 Jun, 2033
(8 years from now)
Active
US10294231 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
(8 years from now)
Active
US10294232 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
(8 years from now)
Active
US10752634 Crystalline forms of a brutons tyrosine kinase inhibitor 03 Jun, 2033
(8 years from now)
Active
US10961251 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
(8 years from now)
Active
US9713617 Crystalline forms of a Bruton's tyrosine kinase inhibitor 03 Jun, 2033
(8 years from now)
Active
US9725455 Crystalline forms of a bruton's tyrosine kinase inhibitor 03 Jun, 2033
(8 years from now)
Active
US10004746
(Pediatric)
Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
(7 years from now)
Active
US10016435
(Pediatric)
Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
(7 years from now)
Active
US10478439
(Pediatric)
Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Dec, 2031
(7 years from now)
Active
US10653696
(Pediatric)
Use of inhibitors of bruton's tyrosine kinase (BTK) 03 Dec, 2031
(7 years from now)
Active
US10751342
(Pediatric)
Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
(7 years from now)
Active
US8754090
(Pediatric)
Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Dec, 2031
(7 years from now)
Active
US8999999
(Pediatric)
Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
(7 years from now)
Active
US9125889
(Pediatric)
Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Dec, 2031
(7 years from now)
Active
US9801881
(Pediatric)
Use of inhibitors of bruton's tyrosine kinase (BTK) 03 Dec, 2031
(7 years from now)
Active
US9801883
(Pediatric)
Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Dec, 2031
(7 years from now)
Active
US9814721
(Pediatric)
Use of inhibitors of bruton'S tyrosine kinase (BTK) 03 Dec, 2031
(7 years from now)
Active
US10004746 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
(6 years from now)
Active
US10016435 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
(6 years from now)
Active
US10478439 Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Jun, 2031
(6 years from now)
Active
US10653696 Use of inhibitors of bruton's tyrosine kinase (BTK) 03 Jun, 2031
(6 years from now)
Active
US10751342 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
(6 years from now)
Active
US11672803 Use of inhibitors of Brutons tyrosine kinase (Btk) 03 Jun, 2031
(6 years from now)
Active
US8754090 Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Jun, 2031
(6 years from now)
Active
US8999999 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
(6 years from now)
Active
US9125889 Use of inhibitors of Bruton's tyrosine kinase (Btk) 03 Jun, 2031
(6 years from now)
Active
US9801881 Use of inhibitors of bruton's tyrosine kinase (BTK) 03 Jun, 2031
(6 years from now)
Active
US9801883 Use of inhibitors of bruton's tyrosine kinase (Btk) 03 Jun, 2031
(6 years from now)
Active
US9814721 Use of inhibitors of bruton'S tyrosine kinase (BTK) 03 Jun, 2031
(6 years from now)
Active
US8008309
(Pediatric)
Inhibitors of bruton's tyrosine kinase 13 May, 2028
(3 years from now)
Active
US8008309 Inhibitors of bruton's tyrosine kinase 13 Nov, 2027
(2 years from now)
Active
US8563563
(Pediatric)
Inhibitors of bruton's tyrosine kinase 26 Oct, 2027
(2 years from now)
Active
US7514444
(Pediatric)
Inhibitors of bruton's tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US8476284
(Pediatric)
Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US8497277
(Pediatric)
Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US8697711
(Pediatric)
Inhibitors of bruton'S tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US8703780
(Pediatric)
Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US8735403
(Pediatric)
Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US8754091
(Pediatric)
Inhibitors of bruton's tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US8952015
(Pediatric)
Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US8957079
(Pediatric)
Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US9181257
(Pediatric)
Inhibitors of Bruton's tyrosine kinase 28 Jun, 2027
(2 years from now)
Active
US8563563 Inhibitors of bruton's tyrosine kinase 26 Apr, 2027
(2 years from now)
Active
US7514444 Inhibitors of bruton's tyrosine kinase 28 Dec, 2026
(2 years from now)
Active
US8476284 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
(2 years from now)
Active
US8497277 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
(2 years from now)
Active
US8697711 Inhibitors of bruton'S tyrosine kinase 28 Dec, 2026
(2 years from now)
Active
US8703780 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
(2 years from now)
Active
US8735403 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
(2 years from now)
Active
US8754091 Inhibitors of bruton's tyrosine kinase 28 Dec, 2026
(2 years from now)
Active
US8952015 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
(2 years from now)
Active
US8957079 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
(2 years from now)
Active
US9181257 Inhibitors of Bruton's tyrosine kinase 28 Dec, 2026
(2 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Imbruvica's drug page


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Pharmacyclics Llc News

AbbVie strengthens its cancer drug portfolio through $21 billion acquisition of Pharmacyclics - Yahoo News UK

10 Jun, 2024

See More