Neurocrine Drug Patent Portfolio

Neurocrine owns 2 orange book drugs protected by 22 US patents Given below is the list of Neurocrine's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10940141 Methods for the administration of certain VMAT2 inhibitors 10 Aug, 2040
Active
US11026931 Methods for the administration of certain VMAT2 inhibitors 14 Aug, 2039
Active
US11654142 Methods for the administration of certain VMAT2 inhibitors 14 Nov, 2038
Active
US11026939 High dosage valbenazine formulation and compositions, methods, and kits related thereto 18 Sep, 2038
Active
US11311532 High dosage valbenazine formulation and compositions, methods, and kits related thereto 18 Sep, 2038
Active
US10857137 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
Active
US10857148 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
Active
US10874648 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
Active
US10912771 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
Active
US10952997 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
Active
US10993941 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
Active
US11040029 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
Active
US11439629 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
Active
US10906902 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1,-a]isoquinolin-2-2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) 22 Dec, 2036
Active
US10906903 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1,-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) 22 Dec, 2036
Active
US10919892 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) 22 Dec, 2036
Active
US10065952 Valbenazine salts and polymorphs thereof 28 Oct, 2036
Active
US10844058 Valbenazine salts and polymorphs thereof 28 Oct, 2036
Active
US10851103 Valbenazine salts and polymorphs thereof 28 Oct, 2036
Active
US10851104 Valbenazine salts and polymorphs thereof 28 Oct, 2036
Active
US8039627 Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto 11 Apr, 2031
Active
US8357697 Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto 08 Nov, 2027
Active


Given below is the list of recent legal activities going on the following drug patents of Neurocrine.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 4th Year, Large Entity 01 Jul, 2024 US10874648
Payment of Maintenance Fee, 4th Year, Large Entity 10 Jun, 2024 US10857137
Payment of Maintenance Fee, 4th Year, Large Entity 10 Jun, 2024 US10857148
Payment of Maintenance Fee, 4th Year, Large Entity 03 Jun, 2024 US10851103
Payment of Maintenance Fee, 4th Year, Large Entity 03 Jun, 2024 US10851104
Payment of Maintenance Fee, 4th Year, Large Entity 24 May, 2024 US10844058
Post Issue Communication - Certificate of Correction 28 Dec, 2023 US11654142
Post Issue Communication - Certificate of Correction 27 Jun, 2023 US8357697
Post Issue Communication - Certificate of Correction 12 Jun, 2023 US8357697
Patent eGrant Notification 23 May, 2023 US11654142
Mail Patent eGrant Notification 23 May, 2023 US11654142
Recordation of Patent eGrant 23 May, 2023 US11654142
Electronic Review 23 May, 2023 US11654142
Email Notification 23 May, 2023 US11654142
Patent Issue Date Used in PTA Calculation 23 May, 2023 US11654142


Neurocrine's Family Patents

Neurocrine drugs have patent protection in a total of 32 countries. It's US patent count contributes only to 27.8% of its total global patent coverage. Click below to unlock the full patent family tree.

Family Patents



Neurocrine Drug List

Given below is the complete list of Neurocrine's drugs and the patents protecting them.


1. Ingrezza

Ingrezza is protected by 22 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10940141 Methods for the administration of certain VMAT2 inhibitors 10 Aug, 2040
(15 years from now)
Active
US11026931 Methods for the administration of certain VMAT2 inhibitors 14 Aug, 2039
(14 years from now)
Active
US11654142 Methods for the administration of certain VMAT2 inhibitors 14 Nov, 2038
(14 years from now)
Active
US11026939 High dosage valbenazine formulation and compositions, methods, and kits related thereto 18 Sep, 2038
(13 years from now)
Active
US11311532 High dosage valbenazine formulation and compositions, methods, and kits related thereto 18 Sep, 2038
(13 years from now)
Active
US10857137 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10857148 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10874648 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10912771 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10952997 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10993941 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US11040029 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US11439629 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10906902 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1,-a]isoquinolin-2-2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) 22 Dec, 2036
(12 years from now)
Active
US10906903 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1,-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) 22 Dec, 2036
(12 years from now)
Active
US10919892 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) 22 Dec, 2036
(12 years from now)
Active
US10065952 Valbenazine salts and polymorphs thereof 28 Oct, 2036
(12 years from now)
Active
US10844058 Valbenazine salts and polymorphs thereof 28 Oct, 2036
(12 years from now)
Active
US10851103 Valbenazine salts and polymorphs thereof 28 Oct, 2036
(12 years from now)
Active
US10851104 Valbenazine salts and polymorphs thereof 28 Oct, 2036
(12 years from now)
Active
US8039627 Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto 11 Apr, 2031
(6 years from now)
Active
US8357697 Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto 08 Nov, 2027
(3 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Ingrezza's drug page


2. Ingrezza Sprinkle

Ingrezza Sprinkle is protected by 22 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10940141 Methods for the administration of certain VMAT2 inhibitors 10 Aug, 2040
(15 years from now)
Active
US11026931 Methods for the administration of certain VMAT2 inhibitors 14 Aug, 2039
(14 years from now)
Active
US11654142 Methods for the administration of certain VMAT2 inhibitors 14 Nov, 2038
(14 years from now)
Active
US11026939 High dosage valbenazine formulation and compositions, methods, and kits related thereto 18 Sep, 2038
(13 years from now)
Active
US11311532 High dosage valbenazine formulation and compositions, methods, and kits related thereto 18 Sep, 2038
(13 years from now)
Active
US10857137 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10857148 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10874648 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10912771 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10952997 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10993941 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US11040029 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US11439629 Methods for the administration of certain VMAT2 inhibitors 10 Oct, 2037
(13 years from now)
Active
US10906902 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1,-a]isoquinolin-2-2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) 22 Dec, 2036
(12 years from now)
Active
US10906903 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1,-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) 22 Dec, 2036
(12 years from now)
Active
US10919892 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate) 22 Dec, 2036
(12 years from now)
Active
US10065952 Valbenazine salts and polymorphs thereof 28 Oct, 2036
(12 years from now)
Active
US10844058 Valbenazine salts and polymorphs thereof 28 Oct, 2036
(12 years from now)
Active
US10851103 Valbenazine salts and polymorphs thereof 28 Oct, 2036
(12 years from now)
Active
US10851104 Valbenazine salts and polymorphs thereof 28 Oct, 2036
(12 years from now)
Active
US8039627 Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto 11 Apr, 2031
(6 years from now)
Active
US8357697 Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto 08 Nov, 2027
(3 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Ingrezza Sprinkle's drug page


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