Merck Drug Patent Portfolio

Merck owns 4 orange book drugs protected by 31 US patents Given below is the list of Merck's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8258132 Pharmaceutical composition of a tachykinin receptor antagonist 26 Sep, 2027
Active
US5994329 Method for inhibiting bone resorption 17 Jan, 2019 Expired
US6015801 Method for inhibiting bone resorption 17 Jan, 2019 Expired
US6225294 Method for inhibiting bone resorption 17 Jan, 2019 Expired
US5994329 Method for inhibiting bone resorption 17 Jul, 2018 Expired
US6015801 Method for inhibiting bone resorption 17 Jul, 2018 Expired
US6225294 Method for inhibiting bone resorption 17 Jul, 2018 Expired
US6096742 Polymorphic form of a tachykinin receptor antagonist 01 Jul, 2018 Expired
US6063811 Compositions for a once day treatment of cyclooxygenase-2 mediated diseases 06 Nov, 2017 Expired
US5952300 Antifungal compositions 28 Sep, 2017 Expired
US6136783 Antifungal compositions 28 Sep, 2017 Expired
US6063811 Compositions for a once day treatment of cyclooxygenase-2 mediated diseases 06 May, 2017 Expired
US5952300 Antifungal compositions 28 Mar, 2017 Expired
US6136783 Antifungal compositions 28 Mar, 2017 Expired
US5691374 Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors 18 Nov, 2015 Expired
US5514650 Aza cyclohexapeptide compounds 26 Jul, 2015 Expired
US5691374 Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors 18 May, 2015 Expired
US5719147 Morpholine and thiomorpholine tachykinin receptor antagonists 17 Apr, 2015 Expired
US5514650 Aza cyclohexapeptide compounds 26 Jan, 2015 Expired
US5462932 Oral liquid alendronate formulations 17 Nov, 2014 Expired
US5462932 Oral liquid alendronate formulations 17 May, 2014 Expired
US5474995 Phenyl heterocycles as cox-2 inhibitors 24 Dec, 2013 Expired
US6239173 3-phenyl-4-(4(methylsulfonyl)phenyl)-2-(5H)-furanone as a cox-2 inhibitor 24 Dec, 2013 Expired
US5378804 Aza cyclohexapeptide compounds 16 Sep, 2013 Expired
US5792746 Aza cyclohexapeptide compounds 16 Sep, 2013 Expired
US5538982 Medical use for tachykinin antagonists 23 Jul, 2013 Expired
US5474995 Phenyl heterocycles as cox-2 inhibitors 24 Jun, 2013 Expired
US6239173 3-phenyl-4-(4(methylsulfonyl)phenyl)-2-(5H)-furanone as a cox-2 inhibitor 24 Jun, 2013 Expired
US5378804 Aza cyclohexapeptide compounds 16 Mar, 2013 Expired
US5792746 Aza cyclohexapeptide compounds 16 Mar, 2013 Expired
US7214692 Medical use for tachykinin antagonists 18 Sep, 2012 Expired


Given below is the list of recent legal activities going on the following drug patents of Merck.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 12th Year, Large Entity 08 Feb, 2024 US8258132
Payment of Maintenance Fee, 8th Year, Large Entity 18 Feb, 2020 US8258132
Expire Patent 05 Jun, 2015 US7214692
Patent Issue Date Used in PTA Calculation 04 Sep, 2012 US8258132
Recordation of Patent Grant Mailed 04 Sep, 2012 US8258132
Issue Notification Mailed 15 Aug, 2012 US8258132
Application Is Considered Ready for Issue 01 Aug, 2012 US8258132
Dispatch to FDC 01 Aug, 2012 US8258132
Issue Fee Payment Received 30 Jul, 2012 US8258132
Issue Fee Payment Verified 30 Jul, 2012 US8258132
Printer Rush- No mailing 14 Jun, 2012 US8258132
Mail Miscellaneous Communication to Applicant 14 Jun, 2012 US8258132
Miscellaneous Communication to Applicant - No Action Count 12 Jun, 2012 US8258132
Pubs Case Remand to TC 07 Jun, 2012 US8258132
Mail Notice of Allowance 03 May, 2012 US8258132


Merck's Drug Patent Litigations

Merck's drugs have been subject to various legal proceedings, including patent litigations. The earliest legal proceeding was initiated on Jul 26, 2005, against patent number US7214692. The petitioner , challenged the validity of this patent, with Russell Michael Hagan et al as the respondent. Click below to track the latest information on how companies are challenging Merck's patents.

Patent Proceeding Filing Date Status Respondent Petitioner
Patent litigations
US7214692 July, 2005 Decision
(18 Jan, 2006)
Russell Michael Hagan et al


Merck Drug Patents' Oppositions Filed in EPO

Merck drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Apr 06, 2009, by Teva Pharmaceutical Industries Ltd.. This opposition was filed on patent number EP02796109A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP02796109A Apr, 2009 Hexal AG Patent maintained as amended
EP02796109A Apr, 2009 Teva Pharmaceutical Industries Ltd. Patent maintained as amended


Merck's Family Patents

Merck drugs have patent protection in a total of 37 countries. It's US patent count contributes only to 7.7% of its total global patent coverage. 34 countries have all of their patents expired or invalidated which has opened up potential generic launch opportunities in these countries. Click below to unlock the full patent family tree.

Family Patents



Merck Drug List

Given below is the complete list of Merck's drugs and the patents protecting them.


1. Cancidas

Cancidas is protected by 10 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5952300
(Pediatric)
Antifungal compositions 28 Sep, 2017
(7 years ago)
Expired
US6136783
(Pediatric)
Antifungal compositions 28 Sep, 2017
(7 years ago)
Expired
US5952300 Antifungal compositions 28 Mar, 2017
(7 years ago)
Expired
US6136783 Antifungal compositions 28 Mar, 2017
(7 years ago)
Expired
US5514650
(Pediatric)
Aza cyclohexapeptide compounds 26 Jul, 2015
(9 years ago)
Expired
US5514650 Aza cyclohexapeptide compounds 26 Jan, 2015
(9 years ago)
Expired
US5378804
(Pediatric)
Aza cyclohexapeptide compounds 16 Sep, 2013
(11 years ago)
Expired
US5792746
(Pediatric)
Aza cyclohexapeptide compounds 16 Sep, 2013
(11 years ago)
Expired
US5378804 Aza cyclohexapeptide compounds 16 Mar, 2013
(11 years ago)
Expired
US5792746 Aza cyclohexapeptide compounds 16 Mar, 2013
(11 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Cancidas's drug page


2. Emend

Emend is protected by 5 patents, out of which 4 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8258132 Pharmaceutical composition of a tachykinin receptor antagonist 26 Sep, 2027
(2 years from now)
Active
US6096742 Polymorphic form of a tachykinin receptor antagonist 01 Jul, 2018
(6 years ago)
Expired
US5719147 Morpholine and thiomorpholine tachykinin receptor antagonists 17 Apr, 2015
(9 years ago)
Expired
US5538982 Medical use for tachykinin antagonists 23 Jul, 2013
(11 years ago)
Expired
US7214692 Medical use for tachykinin antagonists 18 Sep, 2012
(12 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Emend's drug page


3. Fosamax

Fosamax is protected by 8 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5994329
(Pediatric)
Method for inhibiting bone resorption 17 Jan, 2019
(5 years ago)
Expired
US6015801
(Pediatric)
Method for inhibiting bone resorption 17 Jan, 2019
(5 years ago)
Expired
US6225294
(Pediatric)
Method for inhibiting bone resorption 17 Jan, 2019
(5 years ago)
Expired
US5994329 Method for inhibiting bone resorption 17 Jul, 2018
(6 years ago)
Expired
US6015801 Method for inhibiting bone resorption 17 Jul, 2018
(6 years ago)
Expired
US6225294 Method for inhibiting bone resorption 17 Jul, 2018
(6 years ago)
Expired
US5462932
(Pediatric)
Oral liquid alendronate formulations 17 Nov, 2014
(10 years ago)
Expired
US5462932 Oral liquid alendronate formulations 17 May, 2014
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Fosamax's drug page


4. Vioxx

Vioxx is protected by 8 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6063811
(Pediatric)
Compositions for a once day treatment of cyclooxygenase-2 mediated diseases 06 Nov, 2017
(7 years ago)
Expired
US6063811 Compositions for a once day treatment of cyclooxygenase-2 mediated diseases 06 May, 2017
(7 years ago)
Expired
US5691374
(Pediatric)
Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors 18 Nov, 2015
(9 years ago)
Expired
US5691374 Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors 18 May, 2015
(9 years ago)
Expired
US5474995
(Pediatric)
Phenyl heterocycles as cox-2 inhibitors 24 Dec, 2013
(11 years ago)
Expired
US6239173
(Pediatric)
3-phenyl-4-(4(methylsulfonyl)phenyl)-2-(5H)-furanone as a cox-2 inhibitor 24 Dec, 2013
(11 years ago)
Expired
US5474995 Phenyl heterocycles as cox-2 inhibitors 24 Jun, 2013
(11 years ago)
Expired
US6239173 3-phenyl-4-(4(methylsulfonyl)phenyl)-2-(5H)-furanone as a cox-2 inhibitor 24 Jun, 2013
(11 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Vioxx's drug page


Explore Our Curated Drug Screens

Drugs Generating Over $1 Billion in Annual Revenue
Explore the top-performing drugs that dominate the pharmaceutical industry
View List
NCE-1 Patent Expiry in the Next 1 Year
Identify opportunities as new chemical entity (NCE-1) patents approach expiry
View List
Recently Granted Patents in EP
Find the opportunity to file Oppositions
View List

Merck News

Top Pharma Stock Changes in 2021 - BioSpace

27 Nov, 2024

Possible connection between Singulair asthma medication and mental health issues reported - New York Post

23 Nov, 2024

Reuters reports that there may be a potential connection between mental health issues and the previous popular asthma drug, Singulair, developed by Merck.

22 Nov, 2024

Merck (MSD), a prominent multinational pharmaceutical corporation, has officially submitted a...

22 Nov, 2024

See More