Medexus Drug Patent Portfolio

Medexus owns 2 orange book drugs protected by 2 US patents Given below is the list of Medexus's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8664231 Concentrated methotrexate solutions 01 Jun, 2029
Active
US7199162 Use of treosulfan for patient conditioning before bone marrow or blood stem cell transplantation 21 Mar, 2026
Active


Given below is the list of recent legal activities going on the following drug patents of Medexus.

Activity Date Patent Number
Patent litigations
transaction for FDA Determination of Regulatory Review Period 26 Aug, 2025 US7199162
Payment of Maintenance Fee, 12th Year, Large Entity 19 Aug, 2025 US8664231 (Litigated)
Second letter to regulating agency to determine regulatory review period 09 Jul, 2025 US7199162
Letter from FDA or Dept of Agriculture re PTE application 27 Jun, 2025 US7199162
Interim Patent Term Extension Granted 20 Mar, 2025 US7199162
Initial letter Re: PTE Application to regulating agency 13 Mar, 2025 US7199162
Patent Term Extension Application under 35 USC 156 Filed 28 Feb, 2025 US7199162
PTE Interim Patent Extension filed 28 Feb, 2025 US7199162
Interim Patent Term Extension Granted 01 Oct, 2024 US7199162
Interim Patent Term Extension Granted 30 Sep, 2022 US7199162
Interim Patent Term Extension Granted 05 Oct, 2021 US7199162
Post Issue Communication - Certificate of Correction 29 Sep, 2021 US7199162
Payment of Maintenance Fee, 8th Year, Large Entity 05 Aug, 2021 US8664231 (Litigated)
Change in Power of Attorney (May Include Associate POA) 15 Sep, 2020 US7199162
Email Notification 15 Sep, 2020 US7199162


Medexus's Drug Patent Litigations

Medexus's drugs have been subject to various legal proceedings, including patent litigations. The earliest legal proceeding was initiated on Jul 01, 2014, against patent number US8664231. The petitioner Antares Pharma, Inc., challenged the validity of this patent, with Medac Gesellschaft Fur Klinische as the respondent. Click below to track the latest information on how companies are challenging Medexus's patents.

Patent Proceeding Filing Date Status Respondent Petitioner
Patent litigations
US8664231 July, 2016 Final Written Decision
(07 Feb, 2018)
MEDAC GESELLSCHAFT FÜR KLINISCHE SPEZIALPRÄPARATE MBH et al. Koios Pharmaceuticals LLC
US8664231 February, 2016 Terminated-Settled
(08 Dec, 2016)
MEDAC GESELLSCHAFT FÜR KLINISCHE SPEZIALPRÄPARATE MBH Frontier Therapeutics, LLC
US8664231 July, 2014 Terminated-Settled
(30 Apr, 2015)
Medac Gesellschaft Fur Klinische Antares Pharma, Inc.


Medexus Drug Patents' Oppositions Filed in EPO

Medexus drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Sep 15, 2011, by Antares Pharma, Inc.. This opposition was filed on patent number EP07786239A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP07786239A Oct, 2012 Actavis Group ehf Opposition rejected
EP07786239A Sep, 2011 Antares Pharma, Inc. Opposition rejected


Medexus's Family Patents

Medexus drugs have patent protection in a total of 21 countries. It's US patent count contributes only to 23.5% of its total global patent coverage. 1 country has all of their patents expired or invalidated which has opened up potential generic launch opportunities in this particular country. Click below to unlock the full patent family tree.

Family Patents



Medexus Drug List

Given below is the complete list of Medexus's drugs and the patents protecting them.


1. Grafapex

Grafapex is protected by 1 patent, which is still active. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US7199162 Use of treosulfan for patient conditioning before bone marrow or blood stem cell transplantation 21 Mar, 2026
(5 days from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Grafapex's drug page


2. Rasuvo

Rasuvo is protected by 1 patent, which is still active. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8664231 Concentrated methotrexate solutions 01 Jun, 2029
(3 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Rasuvo's drug page


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