Leo Drug Patent Portfolio

Leo owns 8 orange book drugs protected by 43 US patents with Anzupgo having the least patent protection, holding only 1 patent. And Picato with maximum patent protection, holding 16 patents. Given below is the list of Leo's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9789078 Method of topically treating actinic keratosis with ingenol mebutate cycle therapy 15 May, 2033
Active
US10130640 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Dec, 2031
Active
US9119781 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Dec, 2031
Active
US8609647 19 Sep, 2031
Active
US10130640 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
Active
US10617698 Pharmaceutical spray composition comprising a vitamind D analogue and a corticosteroid 10 Jun, 2031
Active
US10660908 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
Active
US10682364 Pharmaceutical spray composition comprising a vitamind D analogue and a corticosteroid 10 Jun, 2031
Active
US10688108 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
Active
US10716799 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
Active
US9119781 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
Active
US9566286 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
Active
US9211259 Antibiotic kit and composition and uses thereof 28 Feb, 2029
Active
US9265725 Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof 08 Dec, 2027
Active
US10117812 Foamable composition combining a polar solvent and a hydrophobic carrier 18 Oct, 2027
Active
US7700076 Penetrating pharmaceutical foam 18 Sep, 2027
Active
US8278292 Therapeutic compositions 06 Jul, 2027
Active
US8372827 Therapeutic compositions 18 Dec, 2026
Active
US8372828 Therapeutic compositions 18 Dec, 2026
Active
US8377919 Therapeutic compositions 18 Dec, 2026
Active
US8536163 Therapeutic compositions 18 Dec, 2026
Active
US8716271 Therapeutic compositions 18 Dec, 2026
Active
US8735375 Therapeutic compositions 18 Dec, 2026
Active
US9820959 Therapeutic compositions 18 Dec, 2026
Active
US9833428 Therapeutic compositions 18 Dec, 2026
Active
US9833429 Therapeutic compositions 18 Dec, 2026
Active
US9861603 Therapeutic compositions 18 Dec, 2026
Active
US8435498 Penetrating pharmaceutical foam 01 Mar, 2024 Expired
US10322085 Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof 24 Oct, 2023 Expired
US8722021 Foamable carriers 24 Oct, 2023 Expired
US8900554 Foamable composition and uses thereof 24 Oct, 2023 Expired
US6387383 Topical low-viscosity gel composition 03 Aug, 2020 Expired
US6753013 Pharmaceutical composition 27 Jan, 2020 Expired
US6787529 Topical composition 27 Jan, 2020 Expired
US6730288 Mousse composition 08 Sep, 2019 Expired
US6844013 Methods of stimulating the immune system 13 Dec, 2018 Expired
US6534070 Composition with azelaic acid 18 Nov, 2018 Expired
US6432452 Anti-cancer compounds 19 Aug, 2018 Expired
US6787161 Anti-cancer compounds 19 Aug, 2018 Expired
US7410656 Anti-cancer compounds 19 Aug, 2018 Expired
US5763426 Crystalline form of a vitamin D analogue 09 Jun, 2015 Expired
USRE39706 Crystalline form of a vitamin D analogue 09 Jun, 2015 Expired
US5665727 Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them 09 Sep, 2014 Expired


Given below is the list of recent legal activities going on the following drug patents of Leo.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 8th Year, Large Entity 01 Jul, 2024 US9566286
Correspondence Address Change 26 Jun, 2024 US8278292 (Litigated)
Correspondence Address Change 26 Jun, 2024 US8536163 (Litigated)
Correspondence Address Change 26 Jun, 2024 US9789078
Correspondence Address Change 26 Jun, 2024 US8377919 (Litigated)
Correspondence Address Change 26 Jun, 2024 US8716271 (Litigated)
Correspondence Address Change 26 Jun, 2024 US9833429
Correspondence Address Change 26 Jun, 2024 US8735375 (Litigated)
Correspondence Address Change 26 Jun, 2024 US9833428
Correspondence Address Change 26 Jun, 2024 US9861603
Correspondence Address Change 26 Jun, 2024 US8372827 (Litigated)
Correspondence Address Change 26 Jun, 2024 US9820959
Correspondence Address Change 26 Jun, 2024 US8372828 (Litigated)
Maintenance Fee Reminder Mailed 20 May, 2024 US8278292 (Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 29 Nov, 2023 US10716799


Leo Drug Patents' Oppositions Filed in EPO

Leo drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Nov 11, 2014, by Sandoz Ag. This opposition was filed on patent number EP06820561A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP11726055A Sep, 2015 Pentafarma Sociedade Técnico-Medicinal S.A. Opposition rejected
EP03772600A Sep, 2015 Henkel AG & Co. KGaA Patent maintained as amended
EP03772600A Dec, 2014 Guderma GmbH Patent maintained as amended
EP06820561A Nov, 2014 Actavis PTC ehf Revoked
EP06820561A Nov, 2014 Galenicum Health S.L. Revoked
EP06820561A Nov, 2014 Sandoz AG Revoked


Leo's Family Patents

Leo drugs have patent protection in a total of 31 countries. It's US patent count contributes only to 43.9% of its total global patent coverage. 6 countries have all of their patents expired or invalidated which has opened up potential generic launch opportunities in these countries. Click below to unlock the full patent family tree.

Family Patents





Clinical Trials

Recent Clinical Trials by Leo:

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
Investigation of Flare and Remission in Subjects With Atopic Dermatitis LEO Pharma NA WITHDRAWN
(Jul, 2019)
PHASE4


Leo Drug List

Given below is the complete list of Leo's drugs and the patents protecting them.


1. Anzupgo

Anzupgo is protected by 1 patent, which is still active. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8609647 19 Sep, 2031
(5 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Anzupgo's drug page


2. Desonate

Desonate is protected by 1 patent, which has expired already. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6387383 Topical low-viscosity gel composition 03 Aug, 2020
(5 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Desonate's drug page


3. Dovonex

Dovonex is protected by 2 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5763426 Crystalline form of a vitamin D analogue 09 Jun, 2015
(10 years ago)
Expired
USRE39706 Crystalline form of a vitamin D analogue 09 Jun, 2015
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Dovonex's drug page


4. Enstilar

Enstilar is protected by 11 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10130640
(Pediatric)
Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Dec, 2031
(5 years from now)
Active
US9119781
(Pediatric)
Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Dec, 2031
(5 years from now)
Active
US10130640 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
(5 years from now)
Active
US10617698 Pharmaceutical spray composition comprising a vitamind D analogue and a corticosteroid 10 Jun, 2031
(5 years from now)
Active
US10660908 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
(5 years from now)
Active
US10682364 Pharmaceutical spray composition comprising a vitamind D analogue and a corticosteroid 10 Jun, 2031
(5 years from now)
Active
US10688108 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
(5 years from now)
Active
US10716799 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
(5 years from now)
Active
US9119781 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
(5 years from now)
Active
US9566286 Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 10 Jun, 2031
(5 years from now)
Active
US6753013 Pharmaceutical composition 27 Jan, 2020
(5 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Enstilar's drug page


5. Finacea

Finacea is protected by 10 patents, out of which 6 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9211259 Antibiotic kit and composition and uses thereof 28 Feb, 2029
(3 years from now)
Active
US9265725 Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof 08 Dec, 2027
(1 year, 10 months from now)
Active
US10117812 Foamable composition combining a polar solvent and a hydrophobic carrier 18 Oct, 2027
(1 year, 9 months from now)
Active
US7700076 Penetrating pharmaceutical foam 18 Sep, 2027
(1 year, 8 months from now)
Active
US8435498 Penetrating pharmaceutical foam 01 Mar, 2024
(1 year, 10 months ago)
Expired
US10322085 Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof 24 Oct, 2023
(2 years ago)
Expired
US8722021 Foamable carriers 24 Oct, 2023
(2 years ago)
Expired
US8900554 Foamable composition and uses thereof 24 Oct, 2023
(2 years ago)
Expired
US6730288 Mousse composition 08 Sep, 2019
(6 years ago)
Expired
US6534070 Composition with azelaic acid 18 Nov, 2018
(7 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Finacea's drug page


Explore Our Curated Drug Screens

Drugs Generating Over $1 Billion in Annual Revenue
Explore the top-performing drugs that dominate the pharmaceutical industry
View List
NCE-1 Patent Expiry in the Next 1 Year
Identify opportunities as new chemical entity (NCE-1) patents approach expiry
View List
Recently Granted Patents in EP
Find the opportunity to file Oppositions
View List

6. Picato

Picato is protected by 16 patents, out of which 4 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9789078 Method of topically treating actinic keratosis with ingenol mebutate cycle therapy 15 May, 2033
(7 years from now)
Active
US8278292 Therapeutic compositions 06 Jul, 2027
(1 year, 5 months from now)
Active
US8372827 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US8372828 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US8377919 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US8536163 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US8716271 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US8735375 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US9820959 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US9833428 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US9833429 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US9861603 Therapeutic compositions 18 Dec, 2026
(11 months from now)
Active
US6844013 Methods of stimulating the immune system 13 Dec, 2018
(7 years ago)
Expired
US6432452 Anti-cancer compounds 19 Aug, 2018
(7 years ago)
Expired
US6787161 Anti-cancer compounds 19 Aug, 2018
(7 years ago)
Expired
US7410656 Anti-cancer compounds 19 Aug, 2018
(7 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Picato's drug page


7. Protopic

Protopic is protected by 1 patent, which has expired already. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5665727 Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them 09 Sep, 2014
(11 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Protopic's drug page


8. Taclonex

Taclonex is protected by 4 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6753013 Pharmaceutical composition 27 Jan, 2020
(5 years ago)
Expired
US6787529 Topical composition 27 Jan, 2020
(5 years ago)
Expired
US5763426 Crystalline form of a vitamin D analogue 09 Jun, 2015
(10 years ago)
Expired
USRE39706 Crystalline form of a vitamin D analogue 09 Jun, 2015
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Taclonex's drug page