Amylyx Drug Patent Portfolio

Amylyx owns 1 orange book drug protected by 5 US patents Given below is the list of Amylyx's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US11583542 Compositions of bile acids and phenylbutyrate compounds 27 Jul, 2040
Active
US10251896 Compositions for improving cell viability and methods of use thereof 24 Dec, 2033
Active
US10857162 Compositions for improving cell viability and methods of use thereof 24 Dec, 2033
Active
US11071742 Compositions for improving cell viability and methods of use thereof 24 Dec, 2033
Active
US9872865 Compositions for improving cell viability and methods of use thereof 24 Dec, 2033
Active


Given below is the list of recent legal activities going on the following drug patents of Amylyx.

Activity Date Patent Number
Patent litigations
Correspondence Address Change 04 Feb, 2026 US10251896
Correspondence Address Change 04 Feb, 2026 US11583542
Correspondence Address Change 04 Feb, 2026 US10857162
Correspondence Address Change 04 Feb, 2026 US11071742
Correspondence Address Change 04 Feb, 2026 US9872865
Correspondence Address Change 02 Feb, 2026 US9872865
Correspondence Address Change 02 Feb, 2026 US11071742
Correspondence Address Change 02 Feb, 2026 US11583542
Correspondence Address Change 02 Feb, 2026 US10857162
Correspondence Address Change 02 Feb, 2026 US10251896
Letter from FDA or Dept of Agriculture re PTE application 29 Aug, 2025 US11071742
Letter from FDA or Dept of Agriculture re PTE application 29 Aug, 2025 US10857162
Letter from FDA or Dept of Agriculture re PTE application 29 Aug, 2025 US10251896
Letter from FDA or Dept of Agriculture re PTE application 29 Aug, 2025 US9872865
Payment of Maintenance Fee, 8th Yr, Small Entity 09 Jul, 2025 US9872865


Amylyx Drug Patents' Oppositions Filed in EPO

Amylyx drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Jan 11, 2021, by Bruschettini S.R.L.. This opposition was filed on patent number EP14775675A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP14775675A Jan, 2021 Lederer & Keller Patentanwälte Partnerschaft mbB Opposition rejected
EP14775675A Jan, 2021 Bruschettini S.r.l. Opposition rejected


Amylyx's Family Patents

Amylyx drugs have patent protection in a total of 22 countries. It's US patent count contributes only to 25.9% of its total global patent coverage. Click below to unlock the full patent family tree.

Family Patents



Amylyx Drug List

Given below is the complete list of Amylyx's drugs and the patents protecting them.


1. Relyvrio

Relyvrio is protected by 5 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US11583542 Compositions of bile acids and phenylbutyrate compounds 27 Jul, 2040
(13 years from now)
Active
US10251896 Compositions for improving cell viability and methods of use thereof 24 Dec, 2033
(7 years from now)
Active
US10857162 Compositions for improving cell viability and methods of use thereof 24 Dec, 2033
(7 years from now)
Active
US11071742 Compositions for improving cell viability and methods of use thereof 24 Dec, 2033
(7 years from now)
Active
US9872865 Compositions for improving cell viability and methods of use thereof 24 Dec, 2033
(7 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Relyvrio's drug page


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Amylyx News

Amylyx's previous ALS medication does not succeed in treating another neurological condition, shifting attention to GLP-1.

27 Aug, 2025

Amylyx removes ALS medication from US market following study indicating no positive effects - KFF Health News

05 Apr, 2024

See More